106 Results for "

cd73

" in MedChemExpress (MCE) Product Catalog:
Products (106)

106 Results for "cd73" in MCE Product Catalog:

Cat. No.: HY-P991443

Target:  

CD73

Research Areas:  

Cancer

IPH5301 is a human IgG1 monoclonal antibody (mAb) targeting NT5E/CD73. IPH5301 has a functionally silent Fc domain, specifically inhibits soluble and membrane CD73 enzyme activity, and restores the proliferation of immune T cells. IPH5301 can be used in anti-tumor immunity research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-172527
Research Areas:  

Cancer

CD73-IN-20 (Compound 5c) is an e5′NT (CD73) inhibitor (IC50: 0.37 μM). CD73-IN-20 also inhibits other ectonucleotidases, with IC50s of 1.12 μM (h-ENPP1), 1.37 μM (h-ENPP3), 1.66 μM (r-e5′NT), 1.48 μM (h-TNAP), respectively. CD73-IN-20 can be used for cancer research .
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Cat. No.: HY-147590
CAS No.: 2766565-88-0
Target:  

CD73

Research Areas:  

Inflammation/Immunology

CD73-IN-9 (compound 2) is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-9 can be used for the study of tumor-related diseases .
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Cat. No.: HY-136978
CAS No.: 2381268-71-7
Purity:  99.07%
Target:  

CD73

Research Areas:  

Inflammation/Immunology Cancer

OP-5244 is a potent and orally active inhibitor of CD73, with an IC50 of 0.25 nM. OP-5244 reverses immunosuppression through blocking of adenosine production, and has the potential for the cancer research .
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Cat. No.: HY-112502A
CAS No.: 104835-70-3
Synonyms: Adenosine 5'-(α,β-methylene)diphosphate disodium
Target:  

CD73

Research Areas:  

Cancer

MethADP disodium is a specific CD73 inhibitor.
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Cat. No.: HY-112502B
CAS No.: 89016-30-8
Synonyms: Adenosine 5'-(α,β-methylene)diphosphate sodium
Target:  

CD73

Research Areas:  

Cancer

MethADP (sodium salt) (Adenosine 5'-(α,β-methylene)diphosphate (sodium)) is a specific CD73 inhibitor.
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Cat. No.: HY-112502C
Purity:  99.03%
Synonyms: Adenosine 5'-(α,β-methylene)diphosphate triammonium
Target:  

CD73

Research Areas:  

Cancer

MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor. MethADP can be used for the research of ATP-adenosine pathway .
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Cat. No.: HY-176203
Target:  

CD73

Research Areas:  

Cancer

XC-12 is an orally active and potent small-molecule CD73 inhibitor (an immune checkpoint) with IC50 values of 12.36 nM and 1.29 nM against soluble and membrane-bound CD73 forms, respectively. XC-12 is promising for research of cancers .
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Cat. No.: HY-147594
CAS No.: 2773423-69-9
Target:  

CD73

Research Areas:  

Cancer

CD73-IN-13 (compound 7) is a potent inhibitor of CD73. CD73 is closely associated with tumor growth, angiogenesis and metastasis. CD73-IN-13 can be used for the study of tumor-related diseases .
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Cat. No.: HY-147593
CAS No.: 2773502-79-5
Target:  

CD73

Research Areas:  

Cancer

CD73-IN-12 (compound 9) is a potent inhibitor of CD73. CD73 is closely associated with tumor growth, angiogenesis and metastasis. CD73-IN-12 can be used for the study of tumor-related diseases . CD73-IN-12 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-147588
CAS No.: 2763709-14-2
Target:  

CD73

Research Areas:  

Cancer

CD73-IN-7 (compound 13) is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-7 can be used for the study of tumor-related diseases .
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Cat. No.: HY-147589
CAS No.: 2763710-08-1
Target:  

CD73

Research Areas:  

Cancer

CD73-IN-8 (compound 57) is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-8 can be used for the study of tumor-related diseases .
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Cat. No.: HY-147591
CAS No.: 2766565-91-5
Target:  

CD73

Research Areas:  

Inflammation/Immunology Cancer

CD73-IN-10 (compound 4) is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-10 can be used for the study of tumor-related diseases .
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Cat. No.: HY-147592
CAS No.: 2766566-11-2
Target:  

CD73

Research Areas:  

Inflammation/Immunology Cancer

CD73-IN-11 (compound 24) is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-11 can be used for the study of tumor-related diseases .
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Cat. No.: HY-175319
Target:  

CD73

Research Areas:  

Cancer

CD73-IN-21 (Compound 12f) is an Ecto-5′-nucleotidase (CD73) inhibitor with Kis of 20 and 302  nM for hCD73 and mCD73, respectively. CD73-IN-21 can be used for cancers like breast cancer research .
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Cat. No.: HY-P991330

Target:  

CD73

Research Areas:  

Cancer

BMS-986179 is a human monoclonal antibody (mAb) targeting NT5E/CD73. BMS-986179 inhibits CD73 enzymatic activity in tumor vasculature and tumor cells. BMS-986179 can be used in advanced solid tumors research .
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Cat. No.: HY-161774
CAS No.: 3080717-78-5
Target:  

CD73

Research Areas:  

Cancer

ST80 is an inhibitor for interaction of OTUD4 and CD73. ST80 decreases CD73 protein level, increases CD73 protein turnover, reduces immune evasion of tumor cells, and thus exhibits antitumor efficacy against immunosuppressive triple-negative breast cancer (TNBC) .
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Cat. No.: HY-162554
CAS No.: 3044090-88-9
Target:  

CD73

Research Areas:  

Inflammation/Immunology Cancer

CD73-IN-15 (compound 12f) is a potent inhibitor of CD73, with the IC50 of 60 nM. CD73-IN-15 plays an important role in cancer research .
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Cat. No.: HY-144209
CAS No.: 2757808-96-9
Target:  

CD73

Research Areas:  

Cancer

CD73-IN-6 is a CD73 inhibitor extracted from patent WO2022007677A1 compound 2. CD73-IN-6 can be used for the research of cancer .
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Cat. No.: HY-162918
Target:  

CD73

Research Areas:  

Cancer

CD73-IN-17 (compound 19) is a CD73 inhibitor with IC50 of 0.1 μM for hCD73. CD73-IN-17 can be used in anti-cancer research .
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