2766565-88-0
Chemical Structure
CD73-IN-9
- CAS No.: 2766565-88-0
- Formula:C14H11F2N5O2
- Molecular Weight:319.27
IUPAC Name: 5-(8-((1S,2S)-2-(difluoromethyl)cyclopropyl)-3-fluoroimidazo[1,2-b]pyridazin-6-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: CCXNIFRVXBFCBQ-SVRRBLITSA-N
SMILES: O=C1NC=C(C(N1)=O)C2=NN3C=NC=C3C([C@H]4C[C@@H]4C(F)F)=C2
Biological Activity: CD73-IN-9 (compound 2) is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-9 can be used for the study of tumor-related diseases[1].
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CD73-IN-9 | CD73-IN-9 (compound 2) is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-9 can be used for the study of tumor-related diseases. | |||||||||||||||||||||
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Keywords
