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Cat. No.: HY-162554

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CD73-IN-15

CD73-IN-15 (compound 12f) is a potent inhibitor of CD73, with the IC₅₀ of 60 nM. CD73-IN-15 plays an important role in cancer research.

For research use only. We do not sell to patients.

CAS No.: 3044090-88-9
Formula: C₂₄H₁₇BrFN₅O₅
Molecular Weight:554.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

CD73-IN-15 Chemical Structure

CAS No.: 3044090-88-9

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Sample (0.1mg)

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Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity

Description

CD73-IN-15 (compound 12f) is a potent inhibitor of CD73, with the IC₅₀ of 60 nM. CD73-IN-15 plays an important role in cancer research^[1].

Chemical Information

CAS No. 3044090-88-9
Molecular Weight 554.32
Formula C₂₄H₁₇BrFN₅O₅
SMILES

FC1=CC(Br)=CC2=C1N=NN2C3=CC=C4C(NN=C4COC(C(O)=O)(C(O)=O)CC5=CC=CC=C5)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cunjian Shi, et al. Discovery of Novel Non-Nucleoside Inhibitors Interacting with Dizinc Ions of CD73. J Med Chem. 2024 May 29. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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