2766565-91-5
Chemical Structure
CD73-IN-10
- CAS No.: 2766565-91-5
- Formula:C15H13F2N5O2
- Molecular Weight:333.29
IUPAC Name: 5-(8-((1S,2S)-2-(difluoromethyl)cyclopropyl)-3-fluoroimidazo[1,2-b]pyridazin-6-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: OJKOKOXUAFZIPF-SVRRBLITSA-N
SMILES: CN1N=CC2=C1N=C(C=C2[C@@H]3[C@@H](C(F)F)C3)C4=CNC(NC4=O)=O
Biological Activity: CD73-IN-10 (compound 4) is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-10 can be used for the study of tumor-related diseases[1].
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CD73-IN-10 | CD73-IN-10 (compound 4) is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-10 can be used for the study of tumor-related diseases. | |||||||||||||||||||||
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Keywords
