415 Results for "

Additive

" in MedChemExpress (MCE) Product Catalog:
Products (415)

415 Results for "Additive" in MCE Product Catalog:

Cat. No.: HY-183761
Research Areas:  

Infection

Antiviral agent 86 is an anti-coronavirus agent. Antiviral agent 86 acts as a binder of coronavirus non-structural protein 15 (nsp15), with a Kd value of 67 μM against human targets. Antiviral agent 86 inhibits the replication of HCoV-229E and SARS-CoV-2. Antiviral agent 86 exerts inhibitory effects at the post-entry lifecycle stage of coronaviruses in host cells and inhibits the formation of viral double-stranded RNA (dsRNA). Antiviral agent 86 exhibits an additive antiviral effect when used in combination with GS-441524. Antiviral agent 86 can be used in studies related to coronavirus infections .
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Cat. No.: HY-Y0488AR
CAS No.: 540-69-2
Synonyms: Ammonium formate (Standard)
Formic acid ammonium (Standard) is the analytical standard of Formic acid ammonium. This product is intended for research and analytical applications. Formic acid ammonium is the ammonium salt form of formic acid, which is an endogenous metabolite. Formic acid ammonium activates the nitric oxide/cyclic guanosine monophosphate (NO/cGMP) signaling pathway in endothelial cells and inhibits calcium ion influx in vascular smooth muscle cells, resulting in vasomotor relaxation. Formic acid ammonium inhibits cytochrome C oxidase (CcO) and disrupts the electron transport chain, leading to ATP depletion. Formic acid ammonium can be used as a feed additive, which can lower the feed pH value, inhibit the growth of microorganisms (such as Escherichia coli, Salmonella), and extend the shelf life of the feed.
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Cat. No.: HY-Y0543R
CAS No.: 620-02-0
5-Methylfurfural (Standard) is the analytical standard of 5-Methylfurfural. This product is intended for research and analytical applications. 5-Methylfurfural is a chemical that can be utilized as food additive, intermediate in the production of agrochemicals, and precursor of certain anti-cancer natural products. 5-Methylfurfural is formed during the photoexposition of ranitidine hydrochloride. 5-Methylfurfural is an organic compound. 5-Methylfurfural has a strong tendency to be further hydrogenated to 2,5-dimethylfuran (DMF). 5-Methylfurfural can predominantly evoke skin inflammation and barrier disintegration. 5-Methylfurfural degrades native DNA through the formation of single-strand breaks .
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Cat. No.: HY-123581R
CAS No.: 81810-66-4
Quinocetone (Standard) is the analytical standard of Quinocetone (HY-123581). This product is used for research and analytical purposes. Quinocetone is an orally active animal feed additive used to increase the meat production of livestock and poultry. Quinocetone exhibits antibacterial activity against a variety of pathogenic microorganisms. Quinocetone exhibits tissue-specific (liver, lymphocyte) toxicity. Quinocetone induces autophagy in cells through the ATF6/DAPK1 pathway. Quinocetone activates the NF-κB and iNOS pathways, leading to cell apoptosis, hepatocyte vacuolar degeneration and fibrosis. Quinocetone can inhibit Nrf2/HO-1 and induce the generation of reactive oxygen species (ROS), leading to oxidative stress and DNA damage.
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Cat. No.: HY-N7402
CAS No.: 6378-65-0
Target:  

Others

Hexyl hexanoate is a fruit aroma component with potential food and beverage additive activity. Hexyl hexanoate is found in alcoholic beverages and is used to blend fruit flavors. Hexyl hexanoate is present in many fruits, Parmesan cheese, alcoholic beverages, and black tea. Hexyl hexanoate is a volatile component produced as a result of fruit ripening. Toxicity assessments of hexyl hexanoate showed that it is not mutagenic and that exposure is below safety thresholds for repeated dose, reproduction, and local respiratory toxicity. Hexyl hexanoate is also below thresholds in skin sensitization assessments, and for phototoxicity and photosensitization, the results showed that it does not present a relevant risk. Hexyl hexanoate is considered non-persistent, non-bioaccumulative, and non-toxic according to the environmental criteria of the International Fragrance Association .
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Cat. No.: HY-W010807R
CAS No.: 540-10-3
Research Areas:  

Others

Hexadecyl palmitate (Standard) is the analytical standard of Hexadecyl palmitate. This product is intended for research and analytical applications. Hexadecyl palmitate is an organic compound commonly used in the cosmetic industry as an emollient, thickener and skin conditioning agent. Cetyl palmitate is derived from a mixture of cetyl alcohol (a fatty alcohol) and palmitic acid (a saturated fatty acid). It is often used in skin care products such as moisturizers, lotions, and creams to improve their texture and Helps them glide smoothly on the skin. In addition to its use in cosmetics, cetyl palmitate is used in other industries including pharmaceuticals, food additives and lubricants. Overall, it's considered safe for use in personal care products, but like any other ingredient, it may cause irritation or an allergic reaction in some people.
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Cat. No.: HY-W013762R
CAS No.: 77-94-1
Research Areas:  

Others

Tributyl citrate (Standard) is the analytical standard of Tributyl citrate. This product is intended for research and analytical applications. Tributyl citrate is a low-toxicity and orally active citrate ester with no genotoxicity or skin sensitizing activity. Tributyl citrate also acts as a plasticizer, solvent, FDA-approved indirect food additive, and topical anesthetic, among other uses. Tributyl citrate induces a needle-prick insensitivity response that lasts for more than 2 hours, and a 5% suspension of it temporarily eliminates the corneal reflex in rabbits. Tributyl citrate causes no significant systemic toxicity in rats and cats at most tested doses, and only may cause growth retardation and gastrointestinal reactions such as diarrhea and nausea at high doses or with repeated oral administration .
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Cat. No.: HY-W127776
CAS No.: 176736-49-5
Synonyms: Ethylenediaminetetraacetic acid zinc disodium tetrahydrate
Zn(II)-EDTA (Ethylenediaminetetraacetic acid zinc) disodium tetrahydrate is a coordinating agent. Zn(II)-EDTA disodium tetrahydrate coordinates with Zn 2+ to modify its solvated structure, provides pre-synthesized EDTA-Zn complexes that release Zn 2+ to repair zinc anode defects under interfacial electric field, adsorbs onto zinc anode surface to block oxygen and water molecules, inhibits corrosion and hydrogen evolution reactions, promotes uniform Zn 2+ deposition, suppresses zinc dendrite formation, and modulates the hydrogen bonding network within the electrolyte. Zn(II)-EDTA disodium tetrahydrate acts as an electrolyte additive to enhance reversibility and stability of zinc anodes in aqueous zinc-ion batteries .
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Cat. No.: HY-W275882
CAS No.: 13179-98-1
Research Areas:  

Endocrinology

1,6-Dimethoxyhexane is an aliphatic ether that serves as a PROTAC linker and fuel additive. 1,6-Dimethoxyhexane is an orally active testicular toxicant. It has no direct toxicity on its own, but exerts toxicity after oxidative metabolism by liver/testicular microsomes to produce 2-Methoxyacetic Acid (MAA). 1,6-Dimethoxyhexane induces apoptosis/necrosis of pachytene spermatocytes, downregulates the expression of HSP70.2, HSP60 and ERp60/PDI A3, and causes spermatogenic tubule degeneration, testicular/thymic atrophy, a sharp decline in epididymal sperm density, and other effects. 1,6-Dimethoxyhexane can be used in studies related to testicular toxicity .
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Cat. No.: HY-W754199
Synonyms: Guanidinoacetic acid-13C
Glycocyamine- 13C (Guanidinoacetic acid- 13C) is the 13C-labeled Glycocyamine (HY-W021448). Glycocyamine is a direct precursor of creatine and an orally active energy metabolism regulator and myogenic differentiation inducer. Glycocyamine can activate the Akt/mTOR/S6K signaling pathway via miR-133a-3p and miR-1a-3p, and stimulate the mRNA expression of myogenic differentiation factor 1 (MyoD) and myopoietin (MyoG). Glycocyamine can increase muscle creatine concentration and maintain ATP homeostasis through the creatine phosphate/creatine kinase system. Glycocyamine can be used in research on feed additives for poultry farming.
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Cat. No.: HY-Y0121R
CAS No.: 103-36-6
Ethyl cinnamate (Standard) is the analytical standard of Ethyl cinnamate. This product is intended for research and analytical applications. Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
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Cat. No.: HY-Y0121S1
CAS No.: 1336882-58-6
Ethyl cinnamate-d7 is deuterated labeled Ethyl cinnamate (HY-Y0121). Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
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Cat. No.: HY-D0008
CAS No.: 633-03-4
Target:  

Bacterial

Research Areas:  

Infection

Brilliant green is a diaminotriphenylmethane compound and cationic dye that serves as a biological stain. Brilliant green exhibits strong antibacterial activity, with significant inhibitory effects on Gram-positive bacteria. The detection wavelength of Brilliant green is λmax = 625 nm .
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Cat. No.: HY-108029
CAS No.: 1298053-61-8
Synonyms: ACH-2684 sodium; Neceprevir sodium
Target:  

HCV HCV Protease

Research Areas:  

Infection

Deldeprevir (ACH-2684; Neceprevir) sodium is a HCV NS3/4A protease inhibitor and resistance inhibitor. Deldeprevir sodium exhibits activity against wild-type genotype 1a and 1b HCV, including mutant strains resistant to other NS3 protease inhibitors. Deldeprevir sodium blocks the emergence of HCV mutant strains resistant to ACH-3422 in vitro, with enhanced efficacy when used in triple combination with ACH-3422 and ACH-3102 (HY-124182). Deldeprevir sodium shows additive antiviral potency when combined with ACH-3422, and exerts antiviral activity against HCV replicons carrying ACH-3102. Deldeprevir sodium is applicable to research related to hepatitis C .
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Cat. No.: HY-B1580
CAS No.: 4075-81-4
Synonyms: Propionic acid calcium
Calcium propionate (Propionic acid calcium) is a calcium salt of Propionic acid with oral activity, which can be hydrolyzed into propionate and calcium ions. Calcium propionate elevates intracellular ROS levels in tumor cells, depletes GSH, reduces mitochondrial membrane potential, and thereby induces tumor cell apoptosis. In mouse colitis models, Calcium propionate modulates inflammatory factors such as IFN-γ, calprotectin, and Pglyrp3, ameliorating intestinal inflammation and metabolic disorders. In ruminants, Calcium propionate serves as a gluconeogenic precursor, regulating rumen fermentation and microbial diversity; in high-fat diet rats, it alters gut microbiota composition and affects blood biochemical parameters. Calcium propionate is commonly used as a food and feed additive, and is also used in research related to hypocalcemia, dyslipidemia, colitis, and lung cancer .
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Cat. No.: HY-W012399R
CAS No.: 88-58-4
2,5-Di-tert-butylhydroquinone (Standard) is the analytical standard of 2,5-Di-tert-butylhydroquinone. This product is intended for research and analytical applications. 2,5-Di-tert-butylhydroquinone (BHQ) (Compound 2), an indirect food additive, is a Sarco/endoplasmic reticulum Ca 2+ ATPase (SERCA) inhibitor with an IC50 of 400 nM. 2,5-Di-tert-butylhydroquinone disrupts the gating function of the residue Glu309 which prevents Ca 2+ from reaching their binding site. 2,5-Di-tert-butylhydroquinone regulates the activity of 5-lipoxygenase and COX-2 (IC50: 1.8 and 14.1 μM for 5-LO and COX-2, respectively) .
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Cat. No.: HY-W021448S
CAS No.: 1173020-63-7
Synonyms: Guanidinoacetic acid-d2
Glycocyamine-d2 (Guanidinoacetic acid-d2) is the deuterium labeled Glycocyamine (HY-W021448). Glycocyamine is a direct precursor of creatine and an orally active energy metabolism regulator and myogenic differentiation inducer. Glycocyamine can activate the Akt/mTOR/S6K signaling pathway via miR-133a-3p and miR-1a-3p, and stimulate the mRNA expression of myogenic differentiation factor 1 (MyoD) and myopoietin (MyoG). Glycocyamine can increase muscle creatine concentration and maintain ATP homeostasis through the creatine phosphate/creatine kinase system. Glycocyamine can be used in research on feed additives for poultry farming.
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Cat. No.: HY-W021448S1
CAS No.: 2483829-93-0
Synonyms: Guanidinoacetic acid-15N,13C2
Glycocyamine- 15N, 13C2 (Guanidinoacetic acid- 15N, 13C2) is the 13C and 15N labeled Glycocyamine (HY-W021448) . Clycocyamine is a direct precursor of creatine and an orally active energy metabolism regulator and myogenic differentiation inducer. Glycocyamine can activate the Akt/mTOR/S6K signaling pathway via miR-133a-3p and miR-1a-3p, and stimulate the mRNA expression of myogenic differentiation factor 1 (MyoD) and myopoietin (MyoG). Glycocyamine can increase muscle creatine concentration and maintain ATP homeostasis through the creatine phosphate/creatine kinase system. Glycocyamine can be used in research on feed additives for poultry farming.
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Cat. No.: HY-Y1219C
CAS No.: 112926-00-8
Silica gel, high-purity grade, 220-440 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
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Cat. No.: HY-Y1219D
CAS No.: 112926-00-8
Silica gel, high-purity grade, 35-70 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
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