4075-81-4
4075-81-4
Chemical Structure
Calcium propionate
Synonym(s): Propionic acid calcium
- CAS No.: 4075-81-4
- Formula:(CH3CH2COO)2Ca
- Molecular Weight:186.22
IUPAC Name: (3-ethyldioxiran-3-yl)calcium propionate
InChIKey: UZIWAEIKTQRQCZ-UHFFFAOYSA-M
SMILES: CCC(O[Ca]C1(CC)OO1)=O
Biological Activity: Calcium propionate (Propionic acid calcium) is a calcium salt of Propionic acid with oral activity, which can be hydrolyzed into propionate and calcium ions. Calcium propionate elevates intracellular ROS levels in tumor cells, depletes GSH, reduces mitochondrial membrane potential, and thereby induces tumor cell apoptosis. In mouse colitis models, Calcium propionate modulates inflammatory factors such as IFN-γ, calprotectin, and Pglyrp3, ameliorating intestinal inflammation and metabolic disorders. In ruminants, Calcium propionate serves as a gluconeogenic precursor, regulating rumen fermentation and microbial diversity; in high-fat diet rats, it alters gut microbiota composition and affects blood biochemical parameters. Calcium propionate is commonly used as a food and feed additive, and is also used in research related to hypocalcemia, dyslipidemia, colitis, and lung cancer[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Calcium propionate | 99.0% | Calcium propionate (Propionic acid calcium) is a calcium salt of Propionic acid with oral activity, which can be hydrolyzed into propionate and calcium ions. Calcium propionate elevates intracellular ROS levels in tumor cells, depletes GSH, reduces mitochondrial membrane potential, and thereby induces tumor cell apoptosis. In mouse colitis models, Calcium propionate modulates inflammatory factors such as IFN-γ, calprotectin, and Pglyrp3, ameliorating intestinal inflammation and metabolic disorders. In ruminants, Calcium propionate serves as a gluconeogenic precursor, regulating rumen fermentation and microbial diversity; in high-fat diet rats, it alters gut microbiota composition and affects blood biochemical parameters. Calcium propionate is commonly used as a food and feed additive, and is also used in research related to hypocalcemia, dyslipidemia, colitis, and lung cancer. | ||||||||||||||||||||
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Calcium propionate, meets analytical specification of E282 (Standard) | ≥98% | Calcium propionate, meets analytical specification of E282 (Standard) (Bioban-C, meets analytical specification of E282 (Standard)) is the analytical standard of Calcium propionate, meets analytical specification of E282 (HY-B1580A). This product is intended for research and analytical applications. Calcium propionate, meets analytical specification of E282 is a calcium salt of Propionic acid with oral activity, which can be hydrolyzed into propionate and calcium ions. Calcium propionate, meets analytical specification of E282 elevates intracellular ROS levels in tumor cells, depletes GSH, reduces mitochondrial membrane potential, and thereby induces tumor cell apoptosis. In mouse colitis models, Calcium propionate, meets analytical specification of E282 modulates inflammatory factors such as IFN-γ, calprotectin, and Pglyrp3, ameliorating intestinal inflammation and metabolic disorders. In ruminants, Calcium propionate, meets analytical specification of E282 serves as a gluconeogenic precursor, regulating rumen fermentation and microbial diversity; in high-fat diet rats, it alters gut microbiota composition and affects blood biochemical parameters. Calcium propionate, meets analytical specification of E282 is commonly used as a food and feed additive, and is also used in research related to hypocalcemia, dyslipidemia, colitis, and lung cancer. | ||||||||||||||||||||
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Calcium propionate, meets analytical specification of E282 | Calcium propionate, meets analytical specification of E282 (Bioban-C, meets analytical specification of E282) is a calcium salt of Propionic acid with oral activity, which can be hydrolyzed into propionate and calcium ions. Calcium propionate, meets analytical specification of E282 elevates intracellular ROS levels in tumor cells, depletes GSH, reduces mitochondrial membrane potential, and thereby induces tumor cell apoptosis. In mouse colitis models, Calcium propionate, meets analytical specification of E282 modulates inflammatory factors such as IFN-γ, calprotectin, and Pglyrp3, ameliorating intestinal inflammation and metabolic disorders. In ruminants, Calcium propionate, meets analytical specification of E282 serves as a gluconeogenic precursor, regulating rumen fermentation and microbial diversity; in high-fat diet rats, it alters gut microbiota composition and affects blood biochemical parameters. Calcium propionate, meets analytical specification of E282 is commonly used as a food and feed additive, and is also used in research related to hypocalcemia, dyslipidemia, colitis, and lung cancer. | |||||||||||||||||||||
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Calcium propionate, United States Pharmacopeia (USP) Reference Standard | Calcium propionate, United States Pharmacopeia (USP) Reference Standard (Bioban-C (Pharmaceutical primary standard, USP)) is a calcium salt of Propionic acid with oral activity, which can be hydrolyzed into propionate and calcium ions. Calcium propionate, United States Pharmacopeia (USP) Reference Standard elevates intracellular ROS levels in tumor cells, depletes GSH, reduces mitochondrial membrane potential, and thereby induces tumor cell apoptosis. In mouse colitis models, Calcium propionate, United States Pharmacopeia (USP) Reference Standard modulates inflammatory factors such as IFN-γ, calprotectin, and Pglyrp3, ameliorating intestinal inflammation and metabolic disorders. In ruminants, Calcium propionate, United States Pharmacopeia (USP) Reference Standard serves as a gluconeogenic precursor, regulating rumen fermentation and microbial diversity; in high-fat diet rats, it alters gut microbiota composition and affects blood biochemical parameters. Calcium propionate, United States Pharmacopeia (USP) Reference Standard is commonly used as a food and feed additive, and is also used in research related to hypocalcemia, dyslipidemia, colitis, and lung cancer. | |||||||||||||||||||||
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References
- [1]. Zhang F, et al. Calcium Propionate Supplementation Has Minor Effects on Major Ruminal Bacterial Community Composition of Early Lactation Dairy Cows. Frontiers in microbiology. 2022;13:847488.
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[2]. Lieshchova M A. Effect of calcium propionate on rats with a high-fat hypercaloric diet. Regulatory Mechanisms in Biosystems, 2023, 14(4): 680-686.
- [3]. Liu Q, et al. Effects of calcium propionate supplementation on lactation performance, energy balance and blood metabolites in early lactation dairy cows. Journal of animal physiology and animal nutrition. 2010 Oct;94(5):605-14.
- [4]. Ghadimi D, et al. Calcium Propionate Alleviates DSS-Induced Colitis and Influences Lipid Profile, Interferon Gamma, Peptidoglycan Recognition Protein 3 and Calprotectin in One-Year-Old Female and Male C57BL/6 Mice. Scientific Journal of Immunology & Immunotherapy, 2017, 2(1): 007-010.
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[5]. Okkay T M. Impact of calcium propionate on cellular behavior in A549 and DMS114 lung cancer cell lines. Turkish Journal of Biochemistry, 2024, 49: 666-673.
