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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
415 Results for "
Additive
" in MedChemExpress (MCE) Product Catalog:
Products (415)
415 Results for "Additive" in MCE Product Catalog:
Cat. No.: HY-W012399
CAS No.: 88-58-4
Research Areas:
2,5-Di-tert-butylhydroquinone (BHQ) (Compound 2), an indirect food additive, is a Sarco/endoplasmic reticulum Ca 2+ ATPase (SERCA) inhibitor with an IC50 of 400 nM. 2,5-Di-tert-butylhydroquinone disrupts the gating function of the residue Glu309 which prevents Ca 2+ from reaching their binding site. 2,5-Di-tert-butylhydroquinone regulates the activity of 5-lipoxygenase and COX-2 (IC50: 1.8 and 14.1 μM for 5-LO and COX-2, respectively) .
Cat. No.: HY-W064918
CAS No.: 1473450-60-0
NITD-304 is an orally active anti-tuberculosis agent. NITD-304 exerts inhibitory and bactericidal activities gainst Mycobacterium tuberculosis and multidrug-resistant Mycobacterium tuberculosis. NITD-304 inhibits mycobacterial cell wall biosynthesis and demonstrates synergistic or additive growth inhibitory activity with select antibacterial agents. NITD-304 shows low risk of cardiotoxicity and drug-drug interactions, with no inhibition of major cytochrome P-450 enzymes or hERG channel. NITD-304 can be used for the research of tuberculosis and multidrug-resistant tuberculosis .
Cat. No.: HY-W134423
CAS No.: 9002-18-0
Cat. No.: HY-129843
CAS No.: 76692-12-1
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CGP-15720 hydrochloride is an orally active imidazolinylurea compound with anticancer activity, which exhibits inhibitory effects on human bronchial carcinoma in nude mice and respiratory tract tumors induced by diethylnitrosamine in Syrian hamsters. CGP-15720 hydrochloride acts via a non-cytotoxic mode of action, reduces tumor area and tumor incidence, and prolongs the survival time of tumor-bearing animals. Its combination with Bleomycin (HY-108345) or CCNU (HY-13669) produces additive antitumor effects. CGP-15720 hydrochloride can be used in cancer-related research such as bronchogenic carcinoma and laryngeal carcinoma .
Cat. No.: HY-D3162
CAS No.: 2390002-31-8
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HMBI is a fluorescent probe that enables dual-color visualization of both the nucleus and mitochondria and monitors apoptosis. HMBI emits green fluorescence in the nucleus with Ex/Em=405/510-560 nm, and red fluorescence in mitochondria with Ex/Em=543/560-660 nm. The localization and emission properties of HMBI depend on subcellular pH and mitochondrial membrane potential. HMBI can serve as a feed additive for in vitro rumen fermentation; it is partially degraded, absorbed or converted into HMB by microorganisms in the system, so as to support microbial protein synthesis, alter the concentration of rumen metabolites and adjust the composition of bacterial communities .
Synonyms: Tricaprin (Standard); Glyceryl tridecanoate (Standard)
Cat. No.: HY-P1032S
CAS No.: 2226467-14-5
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Cat. No.: HY-W010807
CAS No.: 540-10-3
Cat. No.: HY-W013762
CAS No.: 77-94-1
Research Areas:
Tributyl citrate is a low-toxicity and orally active citrate ester with no genotoxicity or skin sensitizing activity. Tributyl citrate also acts as a plasticizer, solvent, FDA-approved indirect food additive, and topical anesthetic, among other uses. Tributyl citrate induces a needle-prick insensitivity response that lasts for more than 2 hours, and a 5% suspension of it temporarily eliminates the corneal reflex in rabbits. Tributyl citrate causes no significant systemic toxicity in rats and cats at most tested doses, and only may cause growth retardation and gastrointestinal reactions such as diarrhea and nausea at high doses or with repeated oral administration .
Cat. No.: HY-W017960R
CAS No.: 1149-23-1
Synonyms: Et-HE (Standard); 1,4-DHP (Standard)
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Diludine (Standard) is the analytical standard of Diludine (HY-W017960). This product is intended for research and analytical applications. Diludine (BNP-7787) is an orally effective feed additive. Diludine reduces the activity of G6PD and increases the level of superoxide dismutase (SOD). Diludine reduces the mutagenic effect of environmental pollutants, protects parental reproductive systems and improves offspring quality. Diludine is mainly applied during the transition period of dairy cows to increase milk yield and milk fat content, and improve health status during parturition. Diludine can be used in animal feeding research .
Cat. No.: HY-W099538R
CAS No.: 123-28-4
Synonyms: Dilauryl 3,3'-Thiodipropionate (Standard)
Research Areas:
Dilauryl thiodipropionate (Standard) is the analytical standard of Dilauryl thiodipropionate. This product is intended for research and analytical applications. Dilauryl thiodipropionate (DLTDP), which is a sulfur-containing antioxidant commonly used to stabilize polymers and plastics against degradation caused by heat, oxygen, and UV light, acts to scavenge free radicals and others that may cause polymer chain scission and cross-linked active substances, in addition, DLTDP has been used as an additive to lubricants, oils and other industrial fluids to improve their oxidation stability, the long hydrocarbon chain in DLTDP makes it low volatility and compatible with many materials and Good compatibility with substrates.
Cat. No.: HY-W250308
CAS No.: 28211-04-3
Synonyms: Epsilon-polylysine (MW 3800-4200); ε-Polylysine (MW 3800-4200); ε-PL (MW 3800-4200)
Carbarsone, also known as p-ureidobenzenearsonic acid, is historically used as an amebicide in human and veterinary medicine and extensively employed in poultry and swine feed, often in combination with antibiotics to prevent conditions like blackhead in turkeys. It exhibits relatively low acute toxicity, prompting investigations into its safety for food additives under the Federal Food, Drug, and Cosmetic Act. Studies aimed at assessing its potential carcinogenicity in laboratory animals have shown negative evidence similar to other arsanilic acid derivatives, suggesting minimal risk under chronic ingestion conditions. Metabolically, carbarsone is converted to arsanilic acid, which has been observed in preliminary studies involving dogs at high doses .
Cat. No.: HY-15947B
CAS No.: 1817728-45-2
Synonyms: GDC-0994 benzenesulfonate
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Ravoxertinib benzenesulfonate (GDC-0994 benzenesulfonate) is an orally active ERK1/2 inhibitor. Ravoxertinib benzenesulfonate inhibits the ERK1/2 MAPK signaling pathway and reduces the expression levels of c-Myc, HK2 and LDHA. Ravoxertinib benzenesulfonate decreases mammosphere formation, and exerts additive and/or superadditive cytotoxicity when combined with Ipatasertib (HY-15186) in 3D tumor sphere models. Ravoxertinib benzenesulfonate can be used in research related to various cancers including breast cancer, melanoma, head and neck cancer, non-small cell lung cancer, ovarian cancer and Merkel cell carcinoma .
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DCPD is an amine substance with both embryotoxicity and teratogenicity, and its total effect ED50 is 0.6 μmol per egg. DCPD induces early and late embryonic death, and causes multiple embryonic malformations including microcephaly, hypoplastic optic cup, eyelid and corneal defects. DCPD can serve as a calcium phosphate additive for biomimetic α-tricalcium phosphate bone cement, which inhibits the transformation of α-tricalcium phosphate into calcium-deficient hydroxyapatite, blocks the release of Gelatins (HY-Y1365), and effectively prolongs the setting time of bone cement. DCPD is applicable to studies related to embryonic malformations .\n
Cat. No.: HY-W017187
CAS No.: 3602-55-9
Research Areas:
2-tert-Butyl-1,4-benzoquinone is a food additive oxidant, an electrophilic metabolite of Butylated hydroxyanisole (HY-B1066), and an antibacterial agent. 2-tert-Butyl-1,4-benzoquinone reduces virulence factors, activates Nrf2, and induces S-arylation of its negative regulator Keap1. 2-tert-Butyl-1,4-benzoquinone induces HO-1. 2-tert-Butyl-1,4-benzoquinone exhibits quorum sensing inhibitory activity against Chromobacterium violaceum .
Cat. No.: HY-W770203
Synonyms: DG(18:1/0:0/18:2)-d5
Cat. No.: HY-123630R
CAS No.: 25956-17-6
Synonyms: FD&C RED NO. 40 (Standard); CI 16035 (Standard)
Target:
Fluorescent Dye Interleukin Related 5-HT Receptor IFNAR Reactive Oxygen Species (ROS) Reference Standards
Research Areas:
Allura Red AC (Standard) is an analytical standard of Allura Red AC. This product is intended for research and analytical applications. Allura Red AC is a food colorant, appearing as a deep red water-soluble powder or granules, used in various applications such as beverages, syrups, candies, and cereals. Allura Red AC can statically quench the intrinsic fluorescence of HSA. Additionally, Allura Red AC is a 5-hydroxytryptamine (5-HT) pathway-associated pro-inflammatory agent, capable of exacerbating experimental colitis. Allura Red AC holds potential for research in inflammatory bowel disease (IBD), intestinal barrier function, and food additive safety .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
