77-94-1
Chemical Structure
Tributyl citrate
- CAS No.: 77-94-1
- Formula:C18H32O7
- Molecular Weight:360.45
IUPAC Name: tributyl 2-hydroxypropane-1,2,3-tricarboxylate
InChIKey: ZFOZVQLOBQUTQQ-UHFFFAOYSA-N
SMILES: O=C(CC(C(OCCCC)=O)(O)CC(OCCCC)=O)OCCCC
Biological Activity: Tributyl citrate is a low-toxicity and orally active citrate ester with no genotoxicity or skin sensitizing activity. Tributyl citrate also acts as a plasticizer, solvent, FDA-approved indirect food additive, and topical anesthetic, among other uses. Tributyl citrate induces a needle-prick insensitivity response that lasts for more than 2 hours, and a 5% suspension of it temporarily eliminates the corneal reflex in rabbits. Tributyl citrate causes no significant systemic toxicity in rats and cats at most tested doses, and only may cause growth retardation and gastrointestinal reactions such as diarrhea and nausea at high doses or with repeated oral administration[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tributyl citrate | 98.33% | Tributyl citrate is a low-toxicity and orally active citrate ester with no genotoxicity or skin sensitizing activity. Tributyl citrate also acts as a plasticizer, solvent, FDA-approved indirect food additive, and topical anesthetic, among other uses. Tributyl citrate induces a needle-prick insensitivity response that lasts for more than 2 hours, and a 5% suspension of it temporarily eliminates the corneal reflex in rabbits. Tributyl citrate causes no significant systemic toxicity in rats and cats at most tested doses, and only may cause growth retardation and gastrointestinal reactions such as diarrhea and nausea at high doses or with repeated oral administration. | ||||||||||||||||||||
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Tributyl citrate (Standard) | 99.78% | Tributyl citrate (Standard) is the analytical standard of Tributyl citrate. This product is intended for research and analytical applications. Tributyl citrate is a low-toxicity and orally active citrate ester with no genotoxicity or skin sensitizing activity. Tributyl citrate also acts as a plasticizer, solvent, FDA-approved indirect food additive, and topical anesthetic, among other uses. Tributyl citrate induces a needle-prick insensitivity response that lasts for more than 2 hours, and a 5% suspension of it temporarily eliminates the corneal reflex in rabbits. Tributyl citrate causes no significant systemic toxicity in rats and cats at most tested doses, and only may cause growth retardation and gastrointestinal reactions such as diarrhea and nausea at high doses or with repeated oral administration. | ||||||||||||||||||||
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Similarity Score 0.79
HY-W010981Acetyl tributyl citrate -
Similarity Score 0.72
HY-W011602Triethyl citrate -
Similarity Score 0.63
HY-W143997Dibutyl malate -
Similarity Score 0.61
HY-112106ADiethyl aminoethyl hexanoate citrate -
Similarity Score 0.61
HY-W856706Glycerol trivalerate -
Similarity Score 0.60
HY-165190Tristearyl citrate -
Similarity Score 0.60
HY-W009188RTriethyl 2-acetoxypropane-1,2,3-tricarboxylate (Standard) -
Similarity Score 0.59
HY-185181Monoethyl citrate -
Similarity Score 0.59
HY-W127534RTricaproin (Standard) -
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References
- [1]. Fiume MM, et al. Safety Assessment of Citric Acid, Inorganic Citrate Salts, and Alkyl Citrate Esters as Used in Cosmetics. Int J Toxicol. 2014;33(2 suppl):16S-46S. [Content Brief]
- [2]. Finkelstein M, et al. Toxicology of the citric acid esters: tributyl citrate, acetyl tributyl citrate, triethyl citrate, and acetyl triethyl citrate[J]. Toxicology and applied pharmacology, 1959, 1(3): 283-298.
