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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
72 Results for "
Prostanoid
" in MedChemExpress (MCE) Product Catalog:
Products (72)
72 Results for "Prostanoid" in MCE Product Catalog:
Cat. No.: HY-113756AR
CAS No.: 41639-83-2
Research Areas:
Latanoprost acid (Standard) is the analytical standard of Latanoprost acid. This product is intended for research and analytical applications. Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor . Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes .
Cat. No.: HY-127162
CAS No.: 69413-73-6
Synonyms: PGK1
Target:
Research Areas:
Prostaglandin K1 (compound 46) is a structurally modified analog of prostacyclin (prostanoid) with an EC50 of 2800 nM for EP1 and a Ki of 2800 nM .
Cat. No.: HY-163091
Target:
Research Areas:
EP4 receptor antagonist 5 is a potent and selective prostanoid EP4 receptor antagonist that can reduce inflammation Freund’s adjuvant (CFA) model .
Cat. No.: HY-119410
CAS No.: 120824-08-0
Synonyms: HN11500
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Linotroban (HN11500), a Sulotroban (HY-158332) derivative, is an orally active, potent non-prostanoid thromboxane receptor antagonist (TXRA) with a strong antiplatelet profile. Linotroban is used as antithrombotic agent .
Cat. No.: HY-14839A
CAS No.: 223490-49-1
Synonyms: CP 533536
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology
Evatanepag sodium is a non-prostanoid, potent and selective EP2 receptor agonist. Evatanepag sodium can induce local bone formation in vivo. Evatanepag sodium can be used in the research of fractures, bone defects, asthma .
Cat. No.: HY-B0577R
CAS No.: 130209-82-4
Synonyms: PHXA41 (Standard)
Research Areas:
Latanoprost (Standard) is the analytical standard of Latanoprost. This product is intended for research and analytical applications. Latanoprost (PHXA41) is a prostaglandin F2α analogue and an agonist for the FP prostanoid receptor, and lowers intraocular-pressure (IOP).
Cat. No.: HY-129922
CAS No.: 773825-80-2
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Prostaglandin I2 is an unstable prostanoid which, through the ‘I prostanoid’ (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki=0.561 nM).1 AFP 07 shows weaker affinity for EP receptors, with Ki values > 100 nM for EP1-3 and > 10 nM for EP4. 16(R)-AFP 07 is an epimer of AFP 07. Its biological properties, particularly through the IP and EP receptors, remain to be evaluated.
Cat. No.: HY-106699
CAS No.: 87440-45-7
Synonyms: CG 4203 sodium
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Research Areas:
Taprostene sodium is a partial agonist at prostanoid prostacyclin (IP) receptors. Taprostene sodium interacts additively with Prostaglandin E2 (PGE2) (HY-101952), ONO-AE1-259 (selective EP2 agonist), and acetylcholine. Taprostene sodium exerts a significant cardioprotection .
Cat. No.: HY-19641
CAS No.: 148436-63-9
Research Areas:
AH13205 is a selective prostanoid EP2-receptor agonist. AH13205 causes concentration-related relaxations of Carbachol (HY-B1208)-contracted trachea. AH13205 causes dose-related protection against Histamine (HY-B1204)-induced increases in respiratory rate .
Cat. No.: HY-B0131S2
CAS No.: 2342573-59-3
Synonyms: Alprostadil-d9; PGE1-d9
Cat. No.: HY-113096S
Synonyms: PGD1-d4
Cat. No.: HY-B0131S
CAS No.: 211105-33-8
Cat. No.: HY-W007888R
CAS No.: 698-27-1
Cat. No.: HY-129284
CAS No.: 209125-28-0
APHS is a specific and covalent COX-2 inhibitor with neuroprotective effects. COX-2 is a prostaglandin (PG) synthetase overexpressed in colorectal cancer (CRC) and has pleiotropic cancer-promoting effects. APHS modifies COX-2 by acetylating the active site (serine 516), thereby inhibiting prostaglandin production. The neuroprotective activity of APHS is inhibited by prostaglandin E2. APHS also co-inhibits the WNT pathway, an anti-tumor mechanism in addition to COX-2 inhibition .
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Prostaglandin D2 methyl ester is a prodrug form of Prostaglandin D2 (HY-101988) that acts as a DP receptor inhibitor. can be used for research on allergic inflammations .
Cat. No.: HY-182513
CAS No.: 459842-29-6
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Research Areas:
ONO-8539 is an orally active prostanoid EP1 receptor antagonist with competitive, insurmountable binding and slow receptor dissociation for long-duration inhibition. ONO-8539 modulates afferent nerve function related to bladder activity, inhibits detrusor overactivity-related contractions, decreases nonvoiding contractions and voiding duration, and increases uroflow rate with ATP (HY-B2176)-induced detrusor overactivity. ONO-8539 attenuates acid-induced heartburn symptoms, extends time to first heartburn sensation, and prevents primary hypersensitivity after distal esophageal acidification. ONO-8539 can be used for the research of overactive bladder and gastroesophageal reflux disease .
Cat. No.: HY-101987A
CAS No.: 75693-75-3
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(Rac)-BW 245C is a Rac isomer of BW 245C (HY-101987 ). BW 245C is a prostanoid DP-receptor (DP1) agonist, can be used to study stroke .
Cat. No.: HY-101987R
CAS No.: 72814-32-5
Research Areas:
BW 245C (Standard) is the analytical standard of BW 245C (HY-101987). This product is intended for research and analytical applications. BW 245C is a prostanoid DP-receptor (DP1) agonist, used to treat stroke.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
