41639-83-2
Chemical Structure
Latanoprost acid
- CAS No.: 41639-83-2
- Formula:C23H34O5
- Molecular Weight:390.51
IUPAC Name: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoic acid
InChIKey: HNPFPERDNWXAGS-NFVOFSAMSA-N
SMILES: O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)CC[C@H](CCC2=CC=CC=C2)O)C/C=C\CCCC(O)=O
Biological Activity: Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor[1]. Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes[1][2].
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Latanoprost acid | 99.43% | Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes. | ||||||||||||||||||||
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Latanoprost acid (Standard) | ≥98% | Latanoprost acid (Standard) is the analytical standard of Latanoprost acid. This product is intended for research and analytical applications. Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes. | ||||||||||||||||||||
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Latanoprost acid-d4 | Latanoprost acid-d4 is used as the internal standard in the HPLC-MS/MS analysis to determine the level of Latanoprost acid (HY-113756A) in aqueous humor samples of eyes. The product specifications provided below refer solely to the active content of Latanoprost acid-d4. |
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Similarity Score 1.00
HY-113756trans-Latanoprost acid -
Similarity Score 1.00
HY-113756Brel-Latanoprost acid -
Similarity Score 0.92
HY-156101Latanoprost amide -
Similarity Score 0.88
HY-129934Latanoprost ethyl amide -
Similarity Score 0.88
HY-12611515(S)-Latanoprost -
Similarity Score 0.88
HY-135163trans-Latanoprost -
Similarity Score 0.88
HY-B0577Latanoprost -
Similarity Score 0.83
HY-11688915-Keto latanoprost acid -
Similarity Score 0.81
HY-13758517-Trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α -
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References
- [1]. Weinreb RN, et al. Effects of prostaglandins on the aqueous humor outflow pathways. Surv Ophthalmol. 2002 Aug;47 Suppl 1:S53-64. [Content Brief]
- [2]. Xu X, et al. The prevention of latanoprost on osteoclastgenesis in vitro and lipopolysaccharide-induced murine calvaria osteolysis in vivo. J Cell Biochem. 2018 Jun;119(6):4680-4691. [Content Brief]
