15(S)-Latanoprost
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.
For research use only. We do not sell to patients.
- CAS No.: 145773-22-4
- Formula: C26H40O5
- Molecular Weight:432.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 145773-22-4
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Molecular Weight 432.59
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Formula C26H40O5
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SMILES
O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)CC[C@@H](CCC2=CC=CC=C2)O)C/C=C\CCCC(OC(C)C)=O
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Synonyms
15-epi Latanoprost
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)