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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
87 Results for "
RNA modification
" in MedChemExpress (MCE) Product Catalog:
Products (87)
87 Results for "RNA modification" in MCE Product Catalog:
Cat. No.: HY-21286
CAS No.: 63264-29-9
Target:
Research Areas:
N2-Isobutyryl-2'-O-methylguanosine is a nucleic acid synthesis intermediate (e.g., used in antisense oligonucleotides, mRNA modification), for example, it is a key monomer for the synthesis of 2'-O-methyl oligoribonucleotides. N2-Isobutyryl-2'-O-methylguanosine enables the final product to form stable double strands with complementary RNA and is not easily degraded by nucleases. N2-Isobutyryl-2'-O-methylguanosine is mainly used in molecular biology research, and can be used to prepare RNA hybridization probes or participate in related biochemical research such as pre-mRNA splicing mechanisms .
Cat. No.: HY-113081S1
Purity: 98.77%
Cat. No.: HY-164581
CAS No.: 2923115-75-5
Target:
Research Areas:
DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite is an RNA phosphoramidite monomer for oligonucleotide synthesis. DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite enables site-specific introduction of 2'-O-C22 lipophilic modification at guanosine positions to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipid solubility and tissue uptake efficiency of dsRNA. DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite can be used for the construction and mechanism research of nucleic acid silencing molecules .
Cat. No.: HY-151829
CAS No.: 2616562-74-2
Target:
Research Areas:
Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Cat. No.: HY-130803
CAS No.: 23067-10-9
Target:
Research Areas:
5-Methyl-5,6-dihydrouridine is a minor constituent in the chromosomal RNA of the rat ascites tumor. 5-Methyl-5,6-dihydrouridine can be used for nucleic acid modification .
Cat. No.: HY-I0626S1
CAS No.: 181517-10-2
Cat. No.: HY-113081AS
Purity: 98.05%
Cat. No.: HY-I0626S
CAS No.: 285978-06-5
Cat. No.: HY-W011209R
CAS No.: 7724-76-7
Synonyms: Riboprine (Standard)
Category:
Cat. No.: HY-113081S
Cat. No.: HY-W125425
CAS No.: 2758-98-7
Synonyms: Methyl piperazine-2-carboxylate; METTL3 activator-1 free base
Research Areas:
CHMA1004 (Methyl piperazine-2-carboxylate; METTL3 activator-1 free base) is a METTL3/METTL14/WTAP methyltransferase complex activator . CHMA1004 exhibits neuroprotective and anxiolytic potential by enhancing m 6A methylation modification of RNA. CHMA1004 promotes HIV replication in an infection context. CHMA1004 can be used in studies related to anxiety disorders and HIV-1 infection .
Cat. No.: HY-163592
CAS No.: 3034746-11-4
Target:
Research Areas:
PRMT5-IN-43 (compound 4A) is a PRMT5 inhibitor. PRMT5-IN-43 can be used in cancer research .
Cat. No.: HY-163593
CAS No.: 3034746-35-2
Target:
Research Areas:
PRMT5-IN-44 (compound 12) is a PRMT5 inhibitor. PRMT5-IN-44 can be used in cancer research .
Cat. No.: HY-160199
CAS No.: 213206-31-6
Target:
Research Areas:
3'-L-Histidyl-AMP is applicable for nucleoside modification (DNA, RNA) .
Cat. No.: HY-160199A
Target:
Research Areas:
3'-L-histidyl-AMP (disodium) is applicable for nucleoside modification (DNA, RNA) .
Cat. No.: HY-18408
CAS No.: 1415238-77-5
Synonyms: FAI
Target:
Research Areas:
5S rRNA modificator is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to that obtained with existing probes; 5S rRNA RNA modification.
Cat. No.: HY-W042357S
CAS No.: 1799795-94-0
Cat. No.: HY-W042357S1
Cat. No.: HY-W042357S2
Cat. No.: HY-W042357S4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
