2758-98-7
Chemical Structure
CHMA1004
Synonym(s): Methyl piperazine-2-carboxylate; METTL3 activator-1 free base
- CAS No.: 2758-98-7
- Formula:C6H12N2O2
- Molecular Weight:144.17
IUPAC Name: methyl piperazine-2-carboxylate
InChIKey: ODQZNBWVRPKMKN-UHFFFAOYSA-N
SMILES: COC(=O)C1CNCCN1
Biological Activity: CHMA1004 (Methyl piperazine-2-carboxylate; METTL3 activator-1 free base) is a METTL3/METTL14/WTAP methyltransferase complex activator. CHMA1004 exhibits neuroprotective and anxiolytic potential by enhancing m6A methylation modification of RNA. CHMA1004 promotes HIV replication in an infection context. CHMA1004 can be used in studies related to anxiety disorders and HIV-1 infection[1][2].
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CHMA1004 | CHMA1004 (Methyl piperazine-2-carboxylate; METTL3 activator-1 free base) is a METTL3/METTL14/WTAP methyltransferase complex activator. CHMA1004 exhibits neuroprotective and anxiolytic potential by enhancing m6A methylation modification of RNA. CHMA1004 promotes HIV replication in an infection context. CHMA1004 can be used in studies related to anxiety disorders and HIV-1 infection. | |||||||||||||||||||||
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[1]. Kanarik M, et al. RNA m6A methyltransferase activator affects anxiety-related behaviours, monoamines and striatal gene expression in the rat. Acta Neuropsychiatr. 2024 Oct 9;37:e52.
[Content Brief] - [2]. Selberg S, et al. HIV Replication Is Increased by RNA Methylation METTL3/METTL14/WTAP Complex Activators. ACS Omega. 2021;6(24):15957-15963. Published 2021 Jun 11. [Content Brief]
Keywords
