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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
60 Results for "
TPPS
" in MedChemExpress (MCE) Product Catalog:
Products (60)
60 Results for "TPPS" in MCE Product Catalog:
Cat. No.: HY-151404
CAS No.: 2787593-12-6
Antitumor agent-76 (Compound TP-P1) is an orally active, rapid-release and water-soluble Triptolide (HY-32735) proagent with antitumor activity .
Cat. No.: HY-158918
CAS No.: 2661108-93-4
Synonyms: 4-CF3-Triphenylphosphonium-DC
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4-CF3-TPP-DC (4-CF3-Triphenylphosphonium-DC) is an inert mitochondrial targeting carrier, that delivers target drugs and probes to mitochondria without causing mitochondrial depolarization and cytotoxicity in cell C2C12 .
Cat. No.: HY-151556
Antifungal agent 45 is with fungicidal activities. Antifungal agent 45 shows excellent characteristics superior to Kresoxim-methyl (HY-125776), in which the activity enhancement against Phytophthora capsici was the most remarkable, with an EC50 value of about 5 μM .
Cat. No.: HY-172342
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MitoA (bromide) is a mitochondria-targeted H2S probe, which can be used to assess relative changes in mitochondrial levels of H2S in vivo. MitoA (bromide) can accumulate inside mitochondria within tissues in vivo due to tryphenylphosphonium (TPP) cation. MitoA (bromide) can be studied in research on myocardial ischemia .
Cat. No.: HY-144825
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Chol-CTPP is a ligand with dual targeting effect on blood-brain barrier (BBB) and glioma cells. Lip-CTPP can be gained by Chol-CTPP and another mitochondria targeting ligand (Chol-TPP). Lip-CTPP is a promising potential carrier to exert the anti-glioma effect of doxorubicin (DOX) and lonidamine (LND) collaboratively. Lip-CTPP elevates the inhibition rate of tumor cell proliferation, migration and invasion, promote apoptosis and necrosis, and interfere with mitochondrial function .
Cat. No.: HY-186242
CAS No.: 3123944-18-0
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Magnolol-C4-TPP bromide is a mitochondria-targeted magnolol derivative with cytotoxic activity against cancer cells. Magnolol-C4-TPP bromide increases ROS levels and slightly reduces mitochondrial membrane potential in colon cancer cells. Magnolol-C4-TPP bromide can be used in the research of colorectal cancer, liver cancer, and breast cancer .
Cat. No.: HY-102007AR
CAS No.: 1131626-47-5
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Gamitrinib TPP hexafluorophosphate (Standard) is the analytical standard of Gamitrinib TPP hexafluorophosphate (HY-102007A). This product is intended for research and analytical applications. Gamitrinib TPP hexafluorophosphate is a Gamitrinib (GA) mitochondrial matrix inhibitor. Gamitrinib TPP hexafluorophosphate is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity.
Cat. No.: HY-122802
CAS No.: 1838592-80-5
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TPP2a bromide is a thioredoxin reductase (TrxR) inhibitor with an IC50 value of 1.16 μM, and also acts as a TrxR-specific fluorescent probe with environment-sensitive fluorescence. TPP2a bromide selectively forms covalent interactions with subcellular mitochondrial TrxR, thereby modifying its Sec498 residue. TPP2a bromide can increase the level of reactive oxygen species (ROS) in cells and induce mitochondrial apoptosis in cancer cells. TPP2a bromide exhibits enhanced cytotoxicity against cancer cell lines. TPP2a bromide can be used in research related to cervical cancer, lung cancer, etc .
Cat. No.: HY-184737
Target:
Drug Derivative Bcl-2 Family Caspase PARP Mitochondrial Metabolism ATP Synthase Reactive Oxygen Species (ROS) Apoptosis
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TPP-C8-CO-DSG bromide is a derivative of Diosgenin (HY-N0177) and an anticancer agent. TPP-C8-CO-DSG bromide downregulates Bcl-2 expression and upregulates Bax expression. TPP-C8-CO-DSG bromide promotes the cleavage of Caspase 9, Caspase 3 and PARP-1. TPP-C8-CO-DSG bromide depolarizes mitochondrial membrane potential, reduces intracellular ATP production, and induces intracellular ROS accumulation. TPP-C8-CO-DSG bromide promotes Apoptosis. TPP-C8-CO-DSG bromide exhibits anticancer activity against prostate cancer, breast cancer, lung adenocarcinoma, cervical cancer and colorectal cancer. TPP-C8-CO-DSG bromide can be used in the research of cervical cancer .
Cat. No.: HY-P992032
Synonyms: BAY-943 antibody
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Cat. No.: HY-183082
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Mal-GFLG-TPP-PPA is a drug-linker conjugate for ADC, and can be used for synthesis of ADCs. Mal-GFLG-TPP-PPA is used in the synthesis of PEG-iPDPA-GFLG-Y-TPPa .
Cat. No.: HY-RS14943
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TPP2 Human Pre-designed siRNA Set A contains three designed siRNAs for TPP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18977
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Tpp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tpp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24220
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Tpp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tpp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P10707
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Cat. No.: HY-P10707A
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Cat. No.: HY-174953C
Cat. No.: HY-174953D
Cat. No.: HY-W035014
CAS No.: 87345-22-0
Synonyms: TPP-OH
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4-(10,15,20-Triphenylporphyrin-5-yl)phenol (TPP-OH) is an intermediate. 4-(10,15,20-Triphenylporphyrin-5-yl)phenol can be used in the development of optical probes .
Cat. No.: HY-103656R
CAS No.: 917-23-7
Synonyms: TPP (Standard); Tetraphenylporphine (Standard); meso-Tetraphenylporphyrin (Standard)
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Tetraphenylporphyrin (Standard) is the analytical standard of Tetraphenylporphyrin (HY-103656). This product is intended for research and analytical applications. Tetraphenylporphyrin (TPP) is a symmetrically substituted porphyrin-based heterocyclic compound and used as a structural block for supramolecular synthesis. Tetraphenylporphyrin derivatives can be used for cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
