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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
49 Results for "
HOXA
" in MedChemExpress (MCE) Product Catalog:
Products (49)
49 Results for "HOXA" in MCE Product Catalog:
Cat. No.: HY-P810365
Synonyms: ABD-B, Abd-B, drosophila, homolog of, D6a9, Homeobox 1G, Homeobox A9, Homeobox protein Hox-1.7, Homeobox protein Hox-1G, Homeobox protein Hox-A9, Homeodomain protein HOXA9, Hox-1.7
Cat. No.: HY-P74879
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: HOXA1; Homeobox Protein Hox-1F; Prev. HOX1F; Hox 1.6-Like Protein; Prev. HOX1; Lab-Like Protein; Homeo Box A1; Homeobox 1F; Homeobox Protein Hox-A1; BSAS; Homeobox A1; HOX A1 Homeodomain Protein
Species:
Human
Source:
E. coli
Cat. No.: HY-P811860
Synonyms: HOX1K, HOXA2, Homeobox protein Hox-A2, Homeobox protein Hox-1K
Cat. No.: HY-100688R
CAS No.: 2029049-79-2
Research Areas:
ML390 (Standard) is the analytical standard of ML390 (HY-100688). This product is intended for research and analytical applications. ML390 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor. ML390 is an inducer of myeloid differentiation and causes myeloid differentiation in murine (ER-HoxA9) and human (U937 and THP1) acute myeloid leukemia (AML) models .
Cat. No.: HY-P811860A
Synonyms: HOX1K, HOXA2, Homeobox protein Hox-A2, Homeobox protein Hox-1K
Cat. No.: HY-115619
Target:
Research Areas:
EPZ004777 formate is an effective and selective DOT1L inhibitor, with IC50 being 0.4 nM. EPZ004777 formate reduces the levels of H3K79me2 and H3K79me1, significantly down-regulating the expression of HOXA9 and MEIS1. EPZ004777 formate selectively inhibits the proliferation of MLL rearrangement cells and promotes the differentiation and subsequent apoptosis (apoptosis) of leukemia cells. EPZ004777 formate can be used for the study of leukemia .
Cat. No.: HY-108350R
CAS No.: 1454920-20-7
Research Areas:
MI-2-2 (Standard) is the analytical standard of MI-2-2 (HY-108350). This product is intended for research and analytical applications. MI-2-2 is a potent menin-MLL inhibitor. MI-2-2 binds to menin with low nanomolar affinity (Kd=22nM) and very effectively disrupts the bivalent protein-protein interaction between menin and MLL. MI-2-2 has specific and very pronounced activity in MLL leukemia cells, including inhibition of cell proliferation, down-regulation of Hoxa9 expression, and differentiation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
