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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
100 Results for "
Clickable Probes
" in MedChemExpress (MCE) Product Catalog:
Products (100)
100 Results for "Clickable Probes" in MCE Product Catalog:
Cat. No.: HY-137124
CAS No.: 2219331-30-1
Target:
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BB-F-Yne is a protein arginine deiminase (PAD) inhibitor with Ki values of PAD1-4.are 2050, 1700, 1100, 3100 M -1min -1 respectively. BB-F-Yne can be used as a click probe to label PAD .
Cat. No.: HY-137125
CAS No.: 2219324-71-5
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BB-Cl-Yne is a protein arginine deiminase (PAD) inhibitor with Ki values of PAD1-4.are 6400, 3600, 10800, 4900 M -1min -1 respectively. BB-Cl-Yne can be used as a click probe to label PAD .
Cat. No.: HY-D2288
CAS No.: 1798306-00-9
Cat. No.: HY-W800696
CAS No.: 2644752-86-1
Cat. No.: HY-W800698
CAS No.: 2006309-79-9
Cat. No.: HY-W800692
CAS No.: 2644752-84-9
Cat. No.: HY-W724743
CAS No.: 727718-93-6
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Losartan azide is a click chemistry reagent containing an azide group and is a synthetic intermediate for the preparation of angiotensin AT1R-targeted renal PET imaging probe [18 F]fluoropyridine-losartan .
Cat. No.: HY-135636
CAS No.: 2748500-17-4
Cat. No.: HY-132913
CAS No.: 2771119-22-1
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Cyclopropenone probe 1 can specifically and efficiently modify a triple-negative breast cancer driver, glutathione S-transferase pi-1 (GSTP1), by covalently binding at the catalytic active site. Cyclopropenone probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-W800704
CAS No.: 1962073-89-7
Cat. No.: HY-155772
CAS No.: 2941609-83-0
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LUF7690 (Compound 9) is a clickable and covalent affinity-based probe (AfBP) that targets the human A3AR (hA3AR). LUF7690 can be used in the detection and characterization of the hA3AR in different types of granulocytes, among other cell types .
Cat. No.: HY-151691
CAS No.: 1676067-48-3
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Trisulfo-Cy3 Methyltetrazine is a click chemistry reagent containing an methyltetrazine group. Methyltetrazine-activated Cy3 probe reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures .
Cat. No.: HY-D2579
Cat. No.: HY-D2802
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FITC-PEG400-N3 is a fluorescent agent conjugated with FITC and an azide group, which can be used to synthesize fluorescent probes via click chemistry reactions. FITC-PEG400-N3 and its related probe molecules can be applied to targeted imaging, tissue distribution and drug delivery studies of prostate cancer (including castration-resistant prostate cancer), such as serving as a subcellular localization tool for GnRH-II binding proteins. Among them, the excitation wavelength of FITC-N3 is approximately 494 nm, and its emission wavelength is approximately 520 nm .
Cat. No.: HY-147115
CAS No.: 79541-46-1
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4-Azidophlorizin is a high affinity probe and photoaffinity label for the glucose transporter in brush border membranes . 4-Azidophlorizin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-148835A
Purity: 99.77%
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Cat. No.: HY-147150
CAS No.: 150424-94-5
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8-Azido-cADPR, with its photoactive azido group, is a potent photoaffinity probe. 8-Azido-cADPR can be used for the identification and characterization of cADPR-binding proteins . 8-Azido-cADPR is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Deg-1 is a bifunctional probe with a cleavage group and a covalent binding group. Deg-1 binds covalently to target nucleic acids and acts as a click degrader to cleave nucleic acid molecules, exhibiting the potential to selectively cleave target nucleic acids intracellularly. Deg-1 contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkynyl groups, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN. Deg-1 can be used in studies related to acute myeloid leukemia and RNA function .
Cat. No.: HY-173390
CAS No.: 2059099-03-3
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BCN-E-BCN is a strained cycloalkyne-based probe designed for detecting protein sulfenylation, the primary intermediate in protein oxidation. This structurally constrained cycloalkyne compound specifically recognizes sulfenic acid groups formed during thiol oxidation, while remaining completely unreactive toward other oxidative states (such as free thiols, sulfinic, or sulfonic acid groups). Researchers can leverage its efficient conjugation with azide-bearing tags through copper-free click chemistry to amplify detection signals. Compared to conventional detection methods, BCN-E-BCN demonstrates superior reaction kinetics and enhanced sensitivity. With these advantages, BCN-E-BCN shows great promise as an effective tool for protein oxidation research .
Cat. No.: HY-W127719
CAS No.: 96087-38-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
