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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
202 Results for "
binding properties
" in MedChemExpress (MCE) Product Catalog:
Products (202)
202 Results for "binding properties" in MCE Product Catalog:
Cat. No.: HY-114582
CAS No.: 110124-49-7
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Lexitropsin is a netropsin derivative which is determined the binding and specificity properties in interaction with DNA and synthetic polynucleotides .
Cat. No.: HY-D0838S
CAS No.: 2309360-05-0
Cat. No.: HY-D0838S1
CAS No.: 2259752-12-8
Cat. No.: HY-136659
CAS No.: 194089-07-1
Ro 04-5595 is a selective antagonist with specific activity against the NR2B subunit of the NMDA receptor. Ro 04-5595 exhibits favorable pharmacokinetic properties in in vitro and in vivo studies, with rapid uptake and clearance. Ro 04-5595 exhibits strong binding in NR2B receptor-enriched regions and low binding in the cerebellum. Ro 04-5595 is able to effectively inhibit specific binding, showing high affinity for the NR2B receptor and a clear ranking of binding affinity with a variety of other compounds .
Cat. No.: HY-B1844
CAS No.: 70124-77-5
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Flucythrinate is a synthetic pyrethroid with endocrine suppressive properties. Flucythrinate showed good binding affinity to the vitamin D nuclear receptor (VDR) with a score of -11.0 kcal/mol. Flucythrinate has been proposed as a multi-target ligand that may interact with several proteins associated with breast cancer. The screening method for Flucythrinate showed good accuracy in binding site prediction and affinity estimation .
Cat. No.: HY-120948
CAS No.: 121548-81-0
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RU 45196 is an 11 beta-substituted 19-norsteroid of the estra-4,9-diene series. RU 45196 displays fluorescence properties (excitation at 480 nm, emission at 525 nm) as well as high binding affinities for the glucocorticoid and progesterone receptors .
Cat. No.: HY-136630
CAS No.: 944154-59-0
Synonyms: SHR110008
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Felotaxel (SHR110008) is a derivate of Docetaxel (HY-B0011), with antitumor activity and specific pharmacokinetic properties in rats. Felotaxel is rapidly distributed to normal tissues. The kidney is the major excretion organ, and its plasma protein binding capacity is nearly linearly related to concentration.
Cat. No.: HY-14319A
CAS No.: 1197329-42-2
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Sazetidine A hydrochloride is a potent ligand for the α4β2 nicotinic acetylcholine receptor, exhibiting high binding affinities and selectivity towards this subtype. Sazetidine A hydrochloride demonstrates promising pharmacological properties that could potentially contribute to the development of therapies targeting nicotinic receptor-related conditions. Sazetidine A hydrochloride has been implicated in studies examining the binding affinities of various analogs, highlighting its significance in understanding subtype selectivity among nAChR ligands.
Cat. No.: HY-123492
CAS No.: 56767-30-7
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Cat. No.: HY-139907A
CAS No.: 2758817-06-8
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DG013B is an epimer of DG013A (HY-139907). DG013B has weak affinity for ERAP1 and ERAP2 and is often used as a negative control to study the binding properties of DG013A and its analogues to ERAP1 and ERAP2 .
Cat. No.: HY-139907C
Purity: 99.57%
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DG013B formate is an epimer of DG013A (HY-139907). DG013B formate has weak affinity for ERAP1 and ERAP2 and is often used as a negative control to study the binding properties of DG013A and its analogues to ERAP1 and ERAP2 .
Cat. No.: HY-106056
CAS No.: 86111-26-4
Synonyms: D 16726
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Zindoxifene is a partial anti-estrogen. Zindoxifene works primarily by binding to estrogen receptors, thereby inhibiting the growth of estrogen-dependent tumor cells. Zindoxifene is able to exhibit the dual properties of estrogen agonists and antagonists and can be used in research and development to target estrogen-dependent tumors, such as prostate and breast cancer .
Cat. No.: HY-119185
CAS No.: 893556-15-5
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AZD-6605 is a potent, reversible inhibitor of MMP2, MMP9, MMP12 and MMP13 with excellent selectivity. During drug development, AZD-6605 was optimized for activity, solubility and DMPK properties against MMP13 by replacing the zinc hydroxide binding group associated with historical inhibitors .
Cat. No.: HY-P2787
CAS No.: 164257-32-3
Pro-Phe-Phe is a tripeptide composed of canonical amino acids that self-assembles into helical amyloid-like assemblies. Pro-Phe-Phe self-assembles into a network of slender, unbranched helical fibrils in phosphate buffer at pH 7.4. Pro-Phe-Phe exhibits amyloid properties, as demonstrated by thioflavin-T binding and a characteristic amyloid kinetics curve .
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5'-GGCACGUAC-CGA-GG-GAGU-GG- UGA -GG-AUGA- -GG-CGA-----GUACGUGC-3', sodium salt
Cat. No.: HY-153848
0 Images
5'-GGCACGUACGAAGGAAGGAUUGGUAUGUGGUAUAUUCGUACGUGCC-3', sodium salt
Cat. No.: HY-153849
Cat. No.: HY-163746
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BuChE-IN-11 (Compound 3b-1) is an selective BuChE inhibitor with an IC50 of 0.44 μM for hBuChE. BuChE-IN-11 has high blood-brain barrier permeability and exhibits strong antioxidant activity due to its free radical scavenging properties. BuChE-IN-11 interacts with the choline binding site, acetyl binding site, and peripheral anionic site, exhibiting submicromolar BuChE inhibitory activity and preventing β-amyloid (Aβ) self-aggregation. BuChE-IN-11 holds promise for research in the field of Alzheimer's disease .
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ERα degrader-2 is a selective estrogen receptor degrader (SERD) with potent binding affinity with ERα (IC50=17.1 nM), good degradation efficacy (EC50=0.3 nM). ERα degrader-2 exhibits favorable pharmacokinetic properties and excellent agentgability, can be used for HER + breast cancer research .
Cat. No.: HY-P2995C
Cat. No.: HY-110024A
CAS No.: 135722-25-7
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S-14506 hydrochloride is a potent 5-HT1A agonist. S-14506 hydrochloride displays dopamine antagonist properties by blocking dopamine D2 receptors. S-14506 hydrochloride inhibits the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. S-14506 hydrochloride has the potential for the research of anxiolytic agent .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
