Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
87 Results for "
CAMKII
" in MedChemExpress (MCE) Product Catalog:
Products (87)
87 Results for "CAMKII" in MCE Product Catalog:
Cat. No.: HY-P76761
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CAMK2A; CaM-Kinase II Alpha Chain; Prev. CAMKA; CaMK-II Subunit Alpha; CAMKIINalpha; Ca2+/Calmodulin-Dependent Protein Kinase II Alpha Subunit; KIAA0968; Calcium/Calmodulin-Dependent Protein Kinase; Calcium/Calmodulin-Dependent Protein Kinase (CaM Kinase)
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-W720917
CAS No.: 41787-69-3
Cat. No.: HY-P810536
Synonyms: Alpha CAMKII; Calcium calmodulin dependent protein kinase II; Calcium/calmodulin dependent protein kinase II alpha B subunit; Calcium/calmodulin dependent protein kinase type II alpha chain; Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; Calcium/calmodulin-dependent protein kinase II alpha; Calcium/calmodulin-dependent protein kinase II-alpha; Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type IIA; CaM kinase II alpha chain
Cat. No.: HY-108649
CAS No.: 1047980-83-5
Target:
P2Y Receptor G-quadruplex Phospholipase PKC Src CaMK PI3K Akt NO Synthase PERK Sodium Channel
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
MRS2768 is a potent, selective, and metabolically stable P2Y2 receptor agonist with an EC50 of 1.89 μM for the human P2Y2 receptor. MRS2768 activates Gq/PLC/PKC signaling, leading to downstream phosphorylation of Akt, eNOS, and ERK, with effects varying by cell type. MRS2768 inhibits ENaC via Gq/PKC/Src/Akt to promote natriuresis and lower blood pressure in the kidney. MRS2768 activates eNOS to increase NO secretion in endothelial cells. MRS2768 drives proliferation via PI3K/Akt in fibroblasts and cancer cells. MRS2768 exerts anti-apoptotic effects through PKC/Src/Akt in cardiomyocytes. MRS2768 can be applied to investigate P2Y2-dependent pathological processes, including acute kidney injury, chronic kidney disease and renal fibrosis, DOCA-salt induced hypertension, myocardial infarction, pulmonary arterial hypertension, pancreatic cancer, cardiac fibrosis, dry eye disease, as well as shear stress-mediated vascular remodeling and atherosclerosis .
Cat. No.: HY-P701720
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CAMK2D; Calcium/Calmodulin-Dependent Protein Kinase; Prev. CAMKD; CaM Kinase II Subunit Delta; Calcium/Calmodulin-Dependent Protein Kinase (CaM Kinase) II Delta; CaM-Kinase II Delta Chain; Calcium/Calmodulin-Dependent Protein Kinase Type II Subunit Delta
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P76762
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CAMK2B; Calcium/Calmodulin-Dependent Protein Kinase (CaM Kinase) II Beta; Prev. CAMKB; Calcium/Calmodulin-Dependent Protein Kinase; CAMK2; Uncharacterized Protein CAMK2B; CAM2; CaM Kinase II Subunit Beta; Calcium/Calmodulin-Dependent Protein Kinase Type I
Species:
Human
Source:
Sf9 insect cells
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
