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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
127 Results for "
CBP/P300
" in MedChemExpress (MCE) Product Catalog:
Products (127)
127 Results for "CBP/P300" in MCE Product Catalog:
Cat. No.: HY-RS03156
Target:
Research Areas:
Crebbp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Crebbp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-174866
CAS No.: 3055107-34-8
Target:
Research Areas:
BT-O2C is a p300 PROTAC degrader. BT-O2C induces p300 degradation via proteasome- and ubiquitin-like modification-dependent pathways, downregulates the expression of CIC::DUX4 sarcoma target genes, and exerts cytotoxicity against such sarcoma cells. BT-O2C can be used in CIC::DUX4 sarcoma-related studies .
Cat. No.: HY-P702904
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KAT2B; K(Lysine) Acetyltransferase 2B; Prev. PCAF; Histone Acetylase PCAF; P/CAF; GCN5L; P300/CBP-Associated Factor; GCN5; Spermidine Acetyltransferase KAT2B; CREBBP-Associated Factor; Histone Acetyltransferase KAT2B; CAF; Lysine Acetyltransferase 2B; His
Species:
Human
Source:
E. coli
Cat. No.: HY-181854
CAS No.: 3124583-65-6
Research Areas:
ZX079 is a dual BRD4 and CBP PROTAC degrader with a BRD4 DC50 value of 0.035 nM and a CBP DC50 value of < 0.02 nM. ZX079 induces dose- and time-dependent degradation of BRD4 and CBP proteins through recruitment of the cereblon E3 ligase. ZX079 induces apoptosis in MV4-11 and MOLM-13 cells, reduces tumor growth in an acute myeloid leukemia xenograft model. ZX079 can be used for the research of acute myeloid leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
