10 Results for "

(±)-Nornicotine

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "(±)-Nornicotine" in MCE Product Catalog:

(±)-Nornicotine
(±)-Nornicotine
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Cat. No.: HY-W002112
CAS No.: 5746-86-1
Synonyms: Nornicotine
Category:  

Alkaloids Pyrrole Alkaloids Neurological Disease Pyridine Alkaloids Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Drug Metabolite nAChR β-catenin

(±)-Nornicotine is a major metabolite of Nicotine. (±)-Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±)-Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±)-Nornicotine supports self-administration behavior. (±)-Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia .
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(S)-Nornicotine
(S)-Nornicotine
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Cat. No.: HY-W040430
CAS No.: 494-97-3
Category:  

Alkaloids Other Diseases Pyridine Alkaloids Endogenous metabolite Disease Research Fields

Target:  

Drug Metabolite Cytochrome P450 nAChR

(S)-Nornicotine is a nicotine metabolite that crosses the blood-brain barrier. (S)-Nornicotine weakly inhibits human CYP2A6 with a Ki >300 μM. (S)-Nornicotine promotes dopamine release in rat striatal and nucleus accumbens slices and increases endogenous DOPAC overflow through a calcium-dependent nAChR pathway that is sensitive to Mecamylamine (HY-B1395A). (S)-Nornicotine reduces behavioral responses maintained by nicotine or sucrose, exerts analgesic effects in persistent inflammatory pain and neuropathic pain models, and enhances the analgesic effect of morphine. (S)-Nornicotine is useful for research on tobacco dependence and pain .
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3-Bromopropan-1-ol
3-Bromopropan-1-ol
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Cat. No.: HY-W007337
CAS No.: 627-18-9
3-Bromopropan-1-ol is an endogenous metabolite. 3-Bromopropan-1-ol is significantly up-regulated during the estrous period of buffaloes. 3-Bromopropan-1-ol acts as an alkylating agent . 3-Bromopropan-1-ol participates in the enantioselective synthesis of nornicotine enantiomers. 3-Bromopropan-1-ol can be used in studies related to estrus detection in buffaloes .
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(±)-Nornicotine-d4
(±)-Nornicotine-d4
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Cat. No.: HY-W002112S
CAS No.: 66148-18-3
Synonyms: Nornicotine-d4
(±)-Nornicotine-d4 is the deuterium labeled (±)-Nornicotine (HY-W002112). (±)-Nornicotine is a major metabolite of Nicotine. (±)-Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±)-Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±)-Nornicotine supports self-administration behavior. (±)-Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia .
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(±)-Nornicotine (Standard)
(±)-Nornicotine (Standard)
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Cat. No.: HY-W002112R
CAS No.: 5746-86-1
Synonyms: Nornicotine (Standard)
Category:  

Alkaloids Pyrrole Alkaloids Pyridine Alkaloids Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite Drug Metabolite nAChR β-catenin

(±)-Nornicotine (Standard) is the analytical standard of (±)-Nornicotine (HY-W002112). This product is intended for research and analytical applications. (±)-Nornicotine is a major metabolite of Nicotine. (±)-Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±)-Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±)-Nornicotine supports self-administration behavior. (±)-Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia .
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(±)-Nornicotine-d7
(±)-Nornicotine-d7
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Cat. No.: HY-W002112S1
Synonyms: Nornicotine-d7
(±)-Nornicotine-d7 is the deuterium labeled (±)-Nornicotine (HY-W002112). (±)-Nornicotine is a major metabolite of Nicotine. (±)-Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±)-Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±)-Nornicotine supports self-administration behavior. (±)-Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia .
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(S)-Nornicotine (Standard)
(S)-Nornicotine (Standard)
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Cat. No.: HY-W040430R
CAS No.: 494-97-3
Category:  

Alkaloids Pyridine Alkaloids Endogenous metabolite

Target:  

Reference Standards Drug Metabolite Cytochrome P450 nAChR

(S)-Nornicotine (Standard) is the analytical standard of (S)-Nornicotine (HY-W040430). This product is intended for research and analytical applications. (S)-Nornicotine is a nicotine metabolite that crosses the blood-brain barrier. (S)-Nornicotine weakly inhibits human CYP2A6 with a Ki >300 μM. (S)-Nornicotine promotes dopamine release in rat striatal and nucleus accumbens slices and increases endogenous DOPAC overflow through a calcium-dependent nAChR pathway that is sensitive to Mecamylamine (HY-B1395A). (S)-Nornicotine reduces behavioral responses maintained by nicotine or sucrose, exerts analgesic effects in persistent inflammatory pain and neuropathic pain models, and enhances the analgesic effect of morphine. (S)-Nornicotine is useful for research on tobacco dependence and pain .
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(S)-Nornicotine hydrochloride
(S)-Nornicotine hydrochloride
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Cat. No.: HY-W040430A
CAS No.: 101832-65-9
Category:  

Alkaloids Pyrrole Alkaloids Other Diseases Pyridine Alkaloids Endogenous metabolite Disease Research Fields

Target:  

Drug Metabolite Cytochrome P450 nAChR

(S)-Nornicotine hydrochloride is a nicotine metabolite that crosses the blood-brain barrier. (S)-Nornicotine hydrochloride weakly inhibits human CYP2A6 with a Ki >300 μM. (S)-Nornicotine hydrochloride promotes dopamine release in rat striatal and nucleus accumbens slices and increases endogenous DOPAC overflow through a calcium-dependent nAChR pathway that is sensitive to Mecamylamine (HY-B1395A). (S)-Nornicotine hydrochloride reduces behavioral responses maintained by nicotine or sucrose, exerts analgesic effects in persistent inflammatory pain and neuropathic pain models, and enhances the analgesic effect of morphine. (S)-Nornicotine hydrochloride is useful for research on tobacco dependence and pain .
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Beta-Zearalanol (Standard)
Beta-Zearalanol (Standard)
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Cat. No.: HY-N6740R
CAS No.: 42422-68-4
Category:  

Microorganisms Macrolide Antibiotics Antibiotics Phenols Polyphenols Disease Research Antibacterial

Target:  

Reference Standards Apoptosis

(±)-Nornicotine (Standard) is the analytical standard of (±)-Nornicotine. This product is intended for research and analytical applications. (±)-Nornicotine is the primary metabolite of nicotine that is formed through demethylation of nicotine in the genus Nicotiana tabacum L. (±)-Nornicotine is a precursor of tobacco-specific nitrosamine N-nitrosonornicotine. (±)-Nornicotine has detrimental effects to human health .
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N-Formylnornicotine
N-Formylnornicotine
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Cat. No.: HY-W189206
CAS No.: 3000-81-5
Target:  

Drug Intermediate

Research Areas:  

Others

N-Formylnornicotine is a key intermediate in the conversion of Nornicotine (HY-W002112) to nicotine .
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