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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
127 Results for "
β-oxidation
" in MedChemExpress (MCE) Product Catalog:
Products (127)
127 Results for "β-oxidation" in MCE Product Catalog:
149
Research Areas:
Etomoxir ((R)-(+)-Etomoxir) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.
149
149 Publications Verification
Cat. No.: HY-50202A
CAS No.: 828934-41-4
Synonyms: (R)-(+)-Etomoxir sodium salt
Research Areas:
Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig .
22
Category:
Natural Products Neurological Disease Endocrine diseases Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Disease markers Nervous System Disorder Disease Research Fields Cancer
Target:
22
22 Cited Publications
Synonyms: (R)-Carnitine hydrochloride; Levocarnitine hydrochloride
Target:
22
22 Cited Publications
Cat. No.: HY-W105518
CAS No.: 36687-82-8
19
Target:
Research Areas:
Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy. Trimetazidine is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
19
19 Cited Publications
Cat. No.: HY-B0968
CAS No.: 13171-25-0
Target:
Research Areas:
Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
10
Target:
5
Target:
Research Areas:
Meldonium (MET-88) functions as a cardioprotective agent by cpmpetetively inhibiting γ-butyrobetaine hydroxylase (BBOX) and carnitine/organic cation transporter type 2 (OCTN2). Meldonium exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Meldonium is a fatty acid oxidation inhibitor .
4
4 Cited Publications
Cat. No.: HY-N0396
CAS No.: 19210-12-9
Category:
Iridoids Terpenoids Pedaliaceae Plants Disease Research Fields Inflammation/Immunology Harpagophytum procumbens
Target:
3
3 Cited Publications
Cat. No.: HY-N0458
CAS No.: 42719-32-4
Category:
Aquifoliaceae Triterpenes Terpenoids Metabolic Disease Parameria laevigata (Juss.) Moldenke Plants Disease Research Fields
Target:
2
2 Cited Publications
Synonyms: Palmitoyl CoA lithium
2
2
2 Cited Publications
Synonyms: O-Acetyl-L-carnitine hydrochloride; ALCAR hydrochloride
Category:
2
2 Cited Publications
Synonyms: O-Acetyl-L-carnitine; ALCAR
Category:
2
2 Cited Publications
Synonyms: DL-Carnitine chloride; DL-Levocarnitine chloride
Target:
2
2 Cited Publications
Target:
1
1
1 Cited Publications
Synonyms: (-)-Lauroylcarnitine
Category:
Immune System Disorder Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields
Target:
1
Category:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
