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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
μ-receptor
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "μ-receptor" in MCE Product Catalog:
Target:
Research Areas:
BMS-986187 is an δ-opioid receptor-selective positive allosteric modulator (PAM) with an EC50 of 0.03 μM and a pKB of 6.02 (～1 μM). BMS-986187 has no observable PAM activity at the μ-receptor (EC50=3 μM) .
Cat. No.: HY-P1701
CAS No.: 74135-04-9
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Research Areas:
Target:
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BMS-986121 is a positive allosteric modulator (PAM) of the μ opioid receptor extracted from patent WO2014107344. BMS-986121 is built on a chemical scaffold representing a new chemotype for μ receptor PAMs .
Cat. No.: HY-106601A
CAS No.: 74685-16-8
Synonyms: LY-150720 hydrochloride
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Research Areas:
Picenadol (LY-150720) hydrochloride is an opioid mixed agonist-antagonist analgesic. Picenadol hydrochloride is an external racemic mixture, where its d-isomer (LY136596) is a potent μ-opioid receptor agonist, and the l-isomer (LY136595) is a weak μ-receptor competitive antagonist, which can inhibit the agonist effect and reduce the risk of dependence. Picenadol hydrochloride has anticholinergic activity .
Cat. No.: HY-P1617
CAS No.: 105496-35-3
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Cat. No.: HY-106601
CAS No.: 79201-85-7
Synonyms: LY-150720
Target:
Research Areas:
Picenadol (LY-150720) is an opioid mixed agonist-antagonist analgesic. Picenadol is an external racemic mixture, where its d-isomer (LY136596) is a potent μ-opioid receptor agonist, and the l-isomer (LY136595) is a weak μ-receptor competitive antagonist, which can inhibit the agonist effect and reduce the risk of dependence. Picenadol has anticholinergic activity .
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RS 39604 is a potent, selective, and orally active 5-HT4 receptor antagonist with a pKi of 9.1 in guinea pig striatal membranes. RS 39604 displays a low affinity (pKi<6.5) for 5-HT1A, 5-HT2C, 5-HT3, α1c, D1, D2, M1, M2, AT1, B1 and opioid mu receptors and moderate affinity for δ1, (pKi=6.8) and δ2 (pKi=7.8) sites .
Cat. No.: HY-182563
CAS No.: 72732-17-3
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Tyr-Ala-N-(1,3-dimethylbutyl)glycinamide is a μ/δ opioid receptor ligand with high μ opioid receptor selectivity and agonist activity. Tyr-Ala-N-(1,3-dimethylbutyl)glycinamide has an IC50 of 237 nM for μ receptors and 1050 nM for δ receptors. Tyr-Ala-N-(1,3-dimethylbutyl)glycinamide shows Ki values of 17 nM for μ receptors and 480 nM for δ receptors. Tyr-Ala-N-(1,3-dimethylbutyl)glycinamide inhibits electrically evoked contractions of guinea pig ileum and mouse vas deferens. Tyr-Ala-N-(1,3-dimethylbutyl)glycinamide serves as a starting compound for structure-activity relationship investigations of μ receptor recognition .
Cat. No.: HY-P77363
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FCAMR; CD351; Fc Alpha And Mu receptor; Fc receptor, IgA, IgM, High Affinity; Fc Alpha/Mu receptor; Fc Fragment Of IgA And IgM receptor; High Affinity Immunoglobulin Alpha And Immunoglobulin Mu Fc receptor; receptor For Fc Fragment Of IgA And IgM; Fcalpha
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P87444A
Synonyms: CD351, FKSG87, FCAMR, High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor, Fc alpha/mu receptor
Cat. No.: HY-P705902
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTPRM; receptor Protein-Tyrosine Kinase; Prev. PTPRL1; Protein-Tyrosine Phosphatase Mu; HR-PTPu; Protein-Tyrosine-Phosphatase; RPTPU; R-PTP-MU; receptor-Type Tyrosine-Protein Phosphatase Mu; R-PTP-Mu; Protein Tyrosine Phosphatase, receptor Type, Mu Polype
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P77364
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: FCMR; Immunoglobulin Mu Fc receptor; Prev. FAIM3; IgM Fc receptor; TOSO; IgM FcR; Fas Apoptotic Inhibitory Molecule 3; IgM Fc Fragment receptor; FcmuR; Fc Mu R; Regulator Of Fas-Induced Apoptosis Toso; Fc Mu receptor; Fc Fragment Of IgM receptor
Species:
Human
Source:
HEK293
Cat. No.: HY-W241255
CAS No.: 27473-62-7
Research Areas:
Neurological Disease Inflammation/Immunology Endocrinology Cancer
2-Aminoindan-2-carboxylic acid is a conformationally restricted Phenylalanine analog and molecular building block. 2-Aminoindan-2-carboxylic acid constitutes a component of allosteric LFA-1 antagonists targeting the LFA-1/ICAM-1 interaction. 2-Aminoindan-2-carboxylic acid serves as a molecular building block for various biologically active peptides, including μ-receptor-selective opioid analogs, activated protein C inhibitors, and histone deacetylase inhibitors. 2-Aminoindan-2-carboxylic acid can be used in the research of autoimmune diseases, inflammatory diseases, opioid receptor-related diseases, antidiuresis-related diseases, and cancers .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
