167710-87-4
Chemical Structure
RS 39604
- CAS No.: 167710-87-4
- Formula:C26H37Cl2N3O6S
- Molecular Weight:590.56
IUPAC Name: N-(2-(4-(3-(4-amino-5-chloro-2-((3,5-dimethoxybenzyl)oxy)phenyl)-3-oxopropyl)piperidin-1-yl)ethyl)methanesulfonamide hydrochloride
InChIKey: QSMYZGMJSGUWPM-UHFFFAOYSA-N
SMILES: CS(=O)(NCCN1CCC(CCC(C2=CC(Cl)=C(N)C=C2OCC3=CC(OC)=CC(OC)=C3)=O)CC1)=O.Cl
Biological Activity: RS 39604 is a potent, selective, and orally active 5-HT4 receptor antagonist with a pKi of 9.1 in guinea pig striatal membranes. RS 39604 displays a low affinity (pKi<6.5) for 5-HT1A, 5-HT2C, 5-HT3, α1c, D1, D2, M1, M2, AT1, B1 and opioid mu receptors and moderate affinity for δ1, (pKi=6.8) and δ2 (pKi=7.8) sites[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RS 39604 | 98.0% | RS 39604 is a potent, selective, and orally active 5-HT4 receptor antagonist with a pKi of 9.1 in guinea pig striatal membranes. RS 39604 displays a low affinity (pKi<6.5) for 5-HT1A, 5-HT2C, 5-HT3, α1c, D1, D2, M1, M2, AT1, B1 and opioid mu receptors and moderate affinity for δ1, (pKi=6.8) and δ2 (pKi=7.8) sites. | ||||||||||||||||||||
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Keywords
