9 Results for "

1-Naphthyl PP1

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "1-Naphthyl PP1" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-13941
CAS No.: 221243-82-9
Purity:  98.96%
Synonyms: 1-NA-PP 1
Target:  

Src PKD

1-Naphthyl PP1 (1-NA-PP 1) is a selective inhibitor of src family kinases and Protein Kinase D. 1-Naphthyl PP1 inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively [1] .
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3
3 Cited Publications
Cat. No.: HY-13941B
CAS No.: 956025-47-1
Purity:  99.83%
Synonyms: 1-NA-PP 1 hydrochloride
Target:  

Src PKD

1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases and Protein Kinase D. 1-Naphthyl PP1 hydrochloride inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively [1] .
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3
3 Cited Publications
Cat. No.: HY-P0171
CAS No.: 664334-36-5
Synonyms: BKT140 (4-fluorobenzoyl); BL-8040; TF14016
Target:  

CXCR

Research Areas:  

Endocrinology Cancer

Motixafortide (BKT140 4-fluorobenzoyl) is a novel CXCR4 antagonist with an IC50 vakue of ~1 nM.
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2
2 Cited Publications
Cat. No.: HY-P0009A
CAS No.: 145672-81-7
Synonyms: SB-75 acetate
Target:  

GnRH Receptor Apoptosis

Research Areas:  

Endocrinology

Cetrorelix (SB-75) acetate is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix acetate inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix acetate prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix acetate is applicable for fertility assistance research [1] .
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1
1 Cited Publications
Cat. No.: HY-P4452
CAS No.: 209006-18-8
Research Areas:  

Endocrinology

PRL 2915 is a potent human somatostatin subtype 2 receptor (hsst2) antagonist with a Ki of 12 nM [1].
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Cat. No.: HY-P0009B
CAS No.: 130143-01-0
Synonyms: SB-75 diacetate
Target:  

GnRH Receptor

Research Areas:  

Neurological Disease Endocrinology

Cetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM [1].
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Cat. No.: HY-131374
CAS No.: 368874-31-1
Target:  

CXCR

Research Areas:  

Cancer

TN14003 is a CXCR4 inhibitor. TN14003 has antitumor activity [1].
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Cat. No.: HY-P2082
CAS No.: 78255-70-6
Target:  

GnRH Receptor

Research Areas:  

Others

[D-pGlu1,D-Phe2,D-NaI3,6]-Gn-RH is a gonadotropin-releasing hormone (Gn-RH) agonist that has a dose-dependent inhibitory activity on progesterone secretion from cultured human granulosa cells.
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Cat. No.: HY-P11893
Research Areas:  

Cancer

PSMA-HK9 is a ligand targeting prostate-specific membrane antigen (PSMA) that binds to PSMA with high affinity, with a Kd value of 4.76 nM. PSMA-HK9 can be labeled with the diagnostic radionuclide 68Ga for imaging applications, and this labeled conjugate exhibits high tumor uptake and low normal tissue uptake in vivo. PSMA-HK9 can be labeled with the radionuclide 177Lu for targeted radionuclide studies, and this labeled conjugate possesses efficient cellular endocytosis and tumor inhibitory activity. PSMA-HK9 can be used in studies related to prostate cancer [1].
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