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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
2′-Deoxy-2′-fluoroadenosine
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "2′-Deoxy-2′-fluoroadenosine" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W039442
CAS No.: 64183-27-3
Target:
2′-Deoxy-2′-fluoroadenosine is a fluorinated deoxyadenosine with antitumor and antiviral activity, able to interfere with viral or cancer cell replication by being incorporated into DNA. 2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP .
17
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Cat. No.: HY-154156
Target:
Research Areas:
2’-Deoxy-2’-fluoroadenosine 5’-monophosphate (triethylammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-136649
Synonyms: AfTP tetralithium, 2′-Fluoro-2′-Deoxy-ATP (tetralithium）
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Research Areas:
2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium is an ATP analog, it exerted a strong but mixed-type inhibition on poly(AU) synthesis.
Cat. No.: HY-P5372A
Research Areas:
Cat. No.: HY-P5443
CAS No.: 224569-84-0
Cat. No.: HY-134033A
Synonyms: 2'-Fluoro dATP sodium
Target:
Research Areas:
2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium (2'-fluoro dATP) is a fluorinated derivative of ATP (HY-B2176). 2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium is a substrate and an inhibitor for E.coli DNA-dependent RNA polymerase, with a Ki of 200 µM .
Cat. No.: HY-154396
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Research Areas:
8-Chloro-2’-deoxy-2’-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-P5373
CAS No.: 237409-87-9
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Cat. No.: HY-P5372
CAS No.: 211190-38-4
Research Areas:
Cat. No.: HY-134033
CAS No.: 73449-07-7
Synonyms: 2'-Fluoro dATP
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Research Areas:
2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate (2'-Fluoro dATP) is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-175135
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Research Areas:
Rp-2'-Deoxy-2'-fluoroadenosine-5'-O-(1-thiotriphosphate) (sodium) is an isomer of the sulfur-containing nucleoide derivative 2’-F-dATP-α-S.
Cat. No.: HY-P1696
CAS No.: 114376-16-8
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Research Areas:
U 70714E is a Renin inhibitor with an IC50 of 3.0 nM. U 70714E is used for the research of renin-related hypertension .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
