2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium
2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium is an ATP analog, it exerted a strong but mixed-type inhibition on poly(AU) synthesis.
For research use only. We do not sell to patients.
- Formula: C10H11FLi4N5O12P3
- Molecular Weight:532.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 532.90
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Formula C10H11FLi4N5O12P3
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SMILES
F[C@@H]([C@@H]1N2C3=C(C(N)=NC=N3)N=C2)[C@H](O)[C@H](O1)COP(OP(OP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O
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Synonyms
AfTP tetralithium, 2′-Fluoro-2′-deoxy-ATP (tetralithium)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kasuya T, et, al. Highly accurate synthesis of the fully 2'-fluoro-modified oligonucleotide by Therminator DNA polymerases. Bioorg Med Chem Lett. 2014 May 1; 24(9): 2134-6. [Content Brief]
[2]. Ishihama A, Enami M, Nishijima Y, Fukui T, Ohtsuka E, Ikehara M. 2'-Deoxy-2'-azidoadenosine triphosphate and 2'-deoxy-2'-fluoroadenosine triphosphate as substrates and inhibitors for Escherichia coli DNA-dependent RNA polymerase. J Biochem. 1980;87(3):825-830. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)