Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
3α-hydroxysteroid dehydrogenase
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "3α-hydroxysteroid dehydrogenase" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P7604
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AKR1C3; Aldo-Keto Reductase Family 1, Member C3 (3-Alpha hydroxysteroid dehydrogenase, Type II), Isoform CRA_a; Prev. HSD17B5; Trans-1,2-Dihydrobenzene-1,2-Diol dehydrogenase; PGFS; Type IIb 3-Alpha hydroxysteroid dehydrogenase; Prostaglandin F Synthase; 3-Alpha-hydroxysteroid dehydrogenase Type 2; KIAA0119; 17-Beta-hydroxysteroid dehydrogenase Type 5; HAKRB; hydroxysteroid (17-Beta) dehydrogenase 5; DDX; Dihydrodiol dehydrogenase Type I; 3-Alpha hydroxysteroid dehydrogenase, Type II; Indanol dehydrogenase; Testosterone 17-Beta-dehydrogenase 5; 3-Alpha-HSD Type 2; Chlordecone Reductase Homolog HAKRb; 17-Beta-HSD 5; Dihydrodiol dehydrogenase X; HluPGFS; Dihydrodiol dehydrogenase 3; HAKRe; 3-Alpha-HSD Type II, Brain; DD-3; HA1753; DDH1; DD3; Aldo-Keto Reductase Family 1 Member C3; Aldo-Keto Reductase Family 1, Member C3 (3-Alpha hydroxysteroid dehydrogenase, Type II)
Species:
Human
Source:
HEK293
Target:
Research Areas:
3α-Hydroxysteroid Dehydrogenase, Microorganism (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism .
Cat. No.: HY-E71717
Target:
Research Areas:
3α-Hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) acts on multiple 3α-hydroxysteroids, such as androsterone and 5 α-dihydrotestosterone.
Cat. No.: HY-E71717A
Target:
Research Areas:
3α-Hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213) acts on multiple 3α-hydroxysteroids.
Cat. No.: HY-E71717B
Target:
Research Areas:
3α-Hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) acts on androsterone and other 3α-hydroxysteroids and on 9-, 11- and 15-hydroxyprostaglandin.
Cat. No.: HY-P2901A
Target:
Research Areas:
3α-Hydroxysteroid Dehydrogenase, Pseudomonas testosteroni (EC 1.1.1.50) belongs to the oxidoreductase family. Its three substrates are androstenedione, NAD+, and NADP+, while its four products are 5α-androstane-3,17-dione, NADH, NADPH, and H+. 3α-Hydroxysteroid Dehydrogenase, Pseudomonas testosteroni, acts on the CH-OH group of the donor molecule, with NAD+ or NADP+ as the acceptor.
Adamantanone (2-Adamantone; 2-Oxoadamantane) serves as a substrate for some alcohol dehydrogenases and also acts as a probe for characterizing substrate-binding pockets. Adamantanone can be reduced by 3α-hydroxysteroid dehydrogenase and 3β-17β-hydroxysteroid dehydrogenase derived from Pseudomonas testosteroni, and it can fit into the conformationally flexible substrate-binding pockets of these enzymes that undergo substrate-induced fit .
Cat. No.: HY-N3115
CAS No.: 139954-00-0
Cat. No.: HY-E71715
Target:
Research Areas:
3α-Hydroxycholanate dehydrogenase (NAD+) (EC 1.1.1.52) acts on other 3α-hydroxysteroids with an acidic side-chain. cf.
Cat. No.: HY-P7469
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AKR1C2; DD/BABP; Prev. DDH2; Aldo-Keto Reductase Family 1, Member C2 (Dihydrodiol dehydrogenase 2; Bile Acid Binding Protein; 3-Alpha hydroxysteroid dehydrogenase, Type III); Prev. TDD; Dihydrodiol dehydrogenase/Bile Acid-Binding Protein; DD2; Trans-1,2-D
Species:
Human
Source:
E. coli
Cat. No.: HY-P75520
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AKR1C2; DD/BABP; Prev. DDH2; Aldo-Keto Reductase Family 1, Member C2 (Dihydrodiol dehydrogenase 2; Bile Acid Binding Protein; 3-Alpha hydroxysteroid dehydrogenase, Type III); Prev. TDD; Dihydrodiol dehydrogenase/Bile Acid-Binding Protein; DD2; Trans-1,2-D
Species:
Human
Source:
E. coli
Cat. No.: HY-P7470
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AKR1C4; Chlordecone Reductase; Prev. CHDR; MGC22581; HAKRA; DD-4; DD4; Aldo-Keto Reductase Family 1, Member C4 (Chlordecone Reductase; 3-Alpha hydroxysteroid dehydrogenase, Type I; Dihydrodiol dehydrogenase 4); CDR; Chlordecone Reductase; 3-Alpha Hydroxys
Species:
Human
Source:
E. coli
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
