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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
3′-Exonuclease
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "3′-Exonuclease" in MCE Product Catalog:
Cat. No.: HY-W570886
CAS No.: 163759-97-5
Target:
Research Areas:
2'-O-MOE-U is a nucleic acid modification group (Phosphoramidite) with 3'-exonuclease inhibitory activity. 2'-O-MOE-U also exhibits gene silencing activity and double-stranded oligonucleotide stability. By forming steric interactions with 3'-exonuclease residues, 2'-O-MOE-U anchors the 3'-end of the siRNA guide strand in the hAgo2 PAZ domain, thereby regulating double-stranded thermal stability and enhancing base-pairing specificity. 2'-O-MOE-U does not induce IFNα production, can be incorporated at multiple sites of siRNA to enhance RNAi activity, and produces a synergistic effect with 2'-F modification. 2'-O-MOE-U has been widely used in studies related to breast cancer and other diseases .
Target:
Research Areas:
Phosphodiesterase II (EC 3.1.16.1), namely phosphodiesterase 2, is mainly involved in the hydrolysis of the important second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), and is often used in biochemical research. Phosphodiesterase II is expressed in a variety of tissues, such as the adrenal medulla, brain, heart, platelets, macrophages and endothelial cells, and is involved in the regulation of many different intracellular processes .
Cat. No.: HY-E70580
CAS No.: 2266626-22-4
Target:
Research Areas:
T5 Exonuclease is a DNA exonuclease that has 5′-3′ exonuclease activity on both single- and double-stranded DNA. T5 Exonuclease also has single-strand endonuclease and 5′-flap endonuclease activity .
Cat. No.: HY-E70404
Research Areas:
FastTaq DNA Polymerase (5'→3' exo-) is a modified DNA polymerase based on Taq DNA Polymerase. FastTaq DNA Polymerase (5'→3' exo-) lacks the 5'→3' exonuclease activity of wild-type Taq. It retains the 5'→3' DNA polymerase activity of wild-type Taq .
Cat. No.: HY-P2937A
Target:
Research Areas:
DNA polymerase, NeoApollonia Thermophilus is a thermostable DNA polymerase from Streptococcus thermophilus that can be used in PCR reactions. DNA polymerase, NeoApollonia Thermophilus has 3’→5’ and 5’→3’ exonuclease activities.
Cat. No.: HY-E70904
Target:
Research Areas:
Terminal Transferase, Calf (EC 2.7.7.31) is a template independent polymerase that catalyzes the addition of deoxynucleotides to the 3' hydroxyl terminus of DNA molecules. Protruding, recessed or blunt-ended double or single-stranded DNA molecules serve as a substrate for Terminal Transferase. Terminal Transferase does not have 5' or 3' exonuclease activity. The addition of Co 2+ in the reacton makes tailing more efficient.
Cat. No.: HY-P703431
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Flap endonuclease; EC:3.1.11.-; FEN; 5'-3' Exonuclease; Exodeoxyribonuclease ; EC:3.1.11.3; D15; exo5; T5.130; T5p128
Species:
Others
Source:
E. coli
Cat. No.: HY-W1061847
Research Areas:
5-VIC Phosphoramidite is a Fluorescent dye and a component of TaqMan probes for nucleic acid detection. 5-VIC Phosphoramidite serves as a 5' reporter dye, which is conjugated to probes targeting the conserved region of the S protein of porcine epidemic diarrhea virus genotype GII, and is used with Eclipse® Dark Quencher for duplex real-time quantitative PCR. 5-VIC Phosphoramidite-labeled probes targeting the Rv0222 gene in the RD4 region specific to Mycobacterium tuberculosis are applied in triplex droplet digital PCR to differentiate mycobacterial strains. During PCR amplification, the 5'→3' exonuclease activity of Taq polymerase mediates the separation of 5-VIC Phosphoramidite from the quencher, thereby generating a detectable fluorescent signal .
Cat. No.: HY-P78019
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: PLD4; Chromosome 14 Open Reading Frame 175; Prev. C14orf175; Choline Phosphatase 4; (S,S)-Bis(Monoacylglycero)Phosphate Synthase PLD4; Spleen Exonuclease; 5'-3' Exonuclease PLD4; SLEB18; Phospholipase D4; PLD 4; Phosphatidylcholine-Hydrolyzing Phospholipa
Species:
Human
Source:
HEK293
Cat. No.: HY-P77821
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: PLD4; Chromosome 14 Open Reading Frame 175; Prev. C14orf175; Choline Phosphatase 4; (S,S)-Bis(Monoacylglycero)Phosphate Synthase PLD4; Spleen Exonuclease; 5'-3' Exonuclease PLD4; SLEB18; Phospholipase D4; PLD 4; Phosphatidylcholine-Hydrolyzing Phospholipa
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
