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A/FujianTongan /196/2009

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50

Inhibitors & Agonists

2

Inhibitory Antibodies

3

Isotope-Labeled Compounds

28

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17600
    Acalabrutinib
    Maximum Cited Publications
    31 Publications Verification

    Calquence; ACP-196

    		 Btk Inflammation/Immunology Cancer
    Acalabrutinib (ACP-196) is an orally active, irreversible, and highly selective second-generation BTK inhibitor. Acalabrutinib binds covalently to Cys481 in the ATP-binding pocket of BTK. Acalabrutinib demonstrates potent on-target effects and efficacy in mouse models of chronic lymphocytic leukemia (CLL). Acalabrutinib can be used for CLL research . Acalabrutinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Acalabrutinib
  • HY-101569
    Darovasertib
    4 Publications Verification

    LXS196; IDE196

    		 PKC Cancer
    Darovasertib (LXS196) is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. Darovasertib has the potential for uveal melanoma research .
    Darovasertib
  • HY-100201
    A-196
    10+ Cited Publications

    		 Histone Methyltransferase Cancer
    A-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively. A-196 inhibits SUV4-20 biochemically in a substrate-competitive manner. A-196 represents a first-in-class chemical probe of SUV4-20 to investigate the role of histone methyltransferases in genomic integrity .
    A-196
  • HY-112939
    Colestilan

    MCI-196; Colestimide

    		 Biochemical Assay Reagents Metabolic Disease
    Colestilan (MCI-196) is a non-absorbed, non-calcium-based phosphate binder and is also a non-metallic, anion exchange resin. Colestilan is orally active and can be used for hypercholesterolaemia research .
    Colestilan
  • HY-B1032
    Dropropizine

    (±)-Dropropizine; UCB-196

    		 Histamine Receptor Neurological Disease
    Dropropizine ((±)-Dropropizine; UCB-196) is an orally effective, peripherally selective antitussive that inhibits the activity of peripheral receptors and afferent nerves in the respiratory tract. Dropropizine acts on the cough reflex pathway, does not pass the blood-brain barrier, and has no central nervous system side effects. Dropropizine mainly regulates the level of sensory neuropeptides and inhibits the afferent signal transmission of the cough reflex, thereby alleviating the symptoms of dry cough, and has both mild local anesthetic and antihistamine activity. Dropropizine is mainly used for symptomatic research on dry cough caused by respiratory diseases .
    Dropropizine
  • HY-17600S
    Acalabrutinib-d4

    ACP-196-d4

    		 Btk Cancer
    Acalabrutinib-d4 (ACP-196-d4) is a deuterium labeled Acalabrutinib. Acalabrutinib (ACP-196) is an orally active, irreversible, and highly selective second-generation BTK inhibitor . Acalabrutinib-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Acalabrutinib-d4
  • HY-U00242
    Indacrinone

    MK-196; Indacrynic acid

    		 Biochemical Assay Reagents Metabolic Disease
    Indacrinone (MK196) is an investigational diuretic which has pronounced saluretic activity in the rat and dog as well as both uricosuric and saluretic activity in the chimpanzee.
    Indacrinone
  • HY-R00389A
    hsa-miR-196a-5p agomir

    		MicroRNA Cancer
    hsa-miR-196a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-196a-5p agomir
    hsa-miR-196a-5p agomir
  • HY-P99435
    Amubarvimab

    BRII-196

    		 SARS-CoV Infection
    Amubarvimab (BRII-196) is a human IgG1 mAb that bind to non-competing epitopes on the receptor binding domain (RBD) of spike protein, with a KD of 5.88 nM. Amubarvimab can effectively neutralize SARS-CoV-2 variants .
    Amubarvimab
  • HY-R00389
    hsa-miR-196a-5p mimic

    		MicroRNA Cancer
    hsa-miR-196a-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-196a-5p mimic
    hsa-miR-196a-5p mimic
  • HY-R00391A
    hsa-miR-196b-5p agomir

    		MicroRNA Cancer
    hsa-miR-196b-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-196b-5p agomir
    hsa-miR-196b-5p agomir
  • HY-R00391
    hsa-miR-196b-5p mimic

    		MicroRNA Cancer
    hsa-miR-196b-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-196b-5p mimic
    hsa-miR-196b-5p mimic
  • HY-RI00391A
    hsa-miR-196b-5p antagomir

    		MicroRNA Cancer
    hsa-miR-196b-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-196b-5p antagomir
    hsa-miR-196b-5p antagomir
  • HY-R00388
    hsa-miR-196a-3p mimic

    		MicroRNA Cancer
    hsa-miR-196a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-196a-3p mimic
    hsa-miR-196a-3p mimic
  • HY-17600R
    Acalabrutinib (Standard)

    ACP-196 (Standard)

    		 Reference Standards Btk Cancer
    Acalabrutinib (Standard) is the analytical standard of Acalabrutinib. This product is intended for research and analytical applications. Acalabrutinib (ACP-196) is an orally active, irreversible, and highly selective second-generation BTK inhibitor. Acalabrutinib binds covalently to Cys481 in the ATP-binding pocket of BTK. Acalabrutinib demonstrates potent on-target effects and efficacy in mouse models of chronic lymphocytic leukemia (CLL) . Acalabrutinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Acalabrutinib (Standard)
  • HY-118590A
    ICRF-196

    		Topoisomerase DNA/RNA Synthesis Apoptosis Fungal Infection Cardiovascular Disease Inflammation/Immunology Cancer
    ICRF-196 is an racemic mixture of the (S,S)- and (R,R)-isomers of ICRF-193 (HY-118590). ICRF-193 is a DNA Topoisomerase II inhibitor. ICRF-193 can inhibit DNA syntheses and induces apoptosis. ICRF-193 exhibits anti-cancer and anti-inflammation effects. ICRF-193 shows cardioprotective effect against anthracycline toxicity to cardiomyocytes. ICRF-193 can be used for the researches of cancer, infection, inflammation and cardiovascular disease, such as acute promyelocytic leukemia .
    ICRF-196
  • HY-156997
    ABX196

    		Interleukin Related Others
    ABX196 is NKT agonist. ABX196 is an analog of the parental compound -GalCer .
    ABX196
  • HY-W757743
    Acalabrutinib-d3

    ACP-196-d3

    		 Isotope-Labeled Compounds Others
    Acalabrutinib-d3 (ACP-196-d3) is the deuterated form of Acalabrutinib (HY-17600). Acalabrutinib (ACP-196) is an orally active, irreversible, highly selective second-generation BTK inhibitor. Acalabrutinib covalently binds to Cys481 in the ATP-binding pocket of BTK. Acalabrutinib shows strong targeting and efficacy in mouse models of chronic lymphocytic leukemia (CLL).
    Acalabrutinib-d3
  • HY-W767656
    Dropropizine-d4

    (±)-Dropropizine-d4; UCB-196-d4

    		 Isotope-Labeled Compounds Others Neurological Disease
    Dropropizine-d4 ((±)-Dropropizine-d4) is deuterium labeled Dropropizine. Dropropizine ((±)-Dropropizine) belongs to the phenylpiperazine group of organic compounds. Dropropizine is a peripheral antitussive agent that acts by inhibiting cough reflex through its action on the peripheral receptors and their afferent conductors .
    Dropropizine-d4
  • HY-P991273
    MP196

    		Antibiotic Bacterial Infection
    MP196 is a cationic hexapeptide antibiotic targeting the bacterial cytoplasmic membrane, which exerts rapid bactericidal activity by disrupting membrane integrity, inhibiting cell respiration and cell wall synthesis. MP196 is promising for research of drug-resistant bacterial infections .
    MP196
  • HY-R04277
    rno-miR-196c-3p mimic

    		MicroRNA Cancer
    rno-miR-196c-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    rno-miR-196c-3p mimic
    rno-miR-196c-3p mimic
  • HY-R02792
    mmu-miR-196a-2-3p mimic

    		MicroRNA Cancer
    mmu-miR-196a-2-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-196a-2-3p mimic
    mmu-miR-196a-2-3p mimic
  • HY-155202
    YJ196

    		Beta-lactamase Others
    YJ196 (Compound 59) is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor .
    YJ196
  • HY-R00387
    hsa-miR-196a-1-3p mimic

    		MicroRNA Cancer
    hsa-miR-196a-1-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-196a-1-3p mimic
    hsa-miR-196a-1-3p mimic
  • HY-R04278A
    rno-miR-196c-5p agomir

    		MicroRNA Cancer
    rno-miR-196c-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    rno-miR-196c-5p agomir
    rno-miR-196c-5p agomir
  • HY-R02792A
    mmu-miR-196a-2-3p agomir

    		MicroRNA Cancer
    mmu-miR-196a-2-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-196a-2-3p agomir
    mmu-miR-196a-2-3p agomir
  • HY-170999
    Antitumor agent-196

    		Caspase Apoptosis Ferroptosis Cancer
    Antitumor agent-196 (Compound 6a (β, β, β)) is an artemisinin-based oligomer with anticancer activity, showing an IC50 of 90 nM against MCF-7 breast cancer cells. Antitumor agent-196 promotes Apoptosis by regulating the Bax-caspase 3 signaling pathway, and induces Ferroptosis through the modulation of key signaling molecules, including GPX4. Antitumor agent-196 holds promising potential for further research in the field of cancer therapy .
    Antitumor agent-196
  • HY-RI04276
    rno-miR-196b-3p inhibitor

    		MicroRNA Cancer
    rno-miR-196b-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    rno-miR-196b-3p inhibitor
    rno-miR-196b-3p inhibitor
  • HY-RI02792
    mmu-miR-196a-2-3p inhibitor

    		MicroRNA Cancer
    mmu-miR-196a-2-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-196a-2-3p inhibitor
    mmu-miR-196a-2-3p inhibitor
  • HY-R04278
    rno-miR-196c-5p mimic

    		MicroRNA Cancer
    rno-miR-196c-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    rno-miR-196c-5p mimic
    rno-miR-196c-5p mimic
  • HY-176769
    E3 Ligase Ligand-linker Conjugate 196

    		E3 Ligase Ligand-Linker Conjugates Others
    E3 Ligase Ligand-linker Conjugate 196 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 196 can be used in the synthesis of PROTAC BRD4 Degrader-38 (HY-175240) .
    E3 Ligase Ligand-linker Conjugate 196
  • HY-158019
    Anticancer agent 196

    		DNA/RNA Synthesis Cancer
    Anticancer agent 196 (compound 1) shows cell cytotoxicity with IC50  values of  7.69 µM and  54.2 µM for HL-60 cells and A549 cells, respectively. Anticancer agent 196 can induce DNA damage .
    Anticancer agent 196
  • HY-163397
    Antibacterial agent 196

    		Fungal Infection
    Antibacterial agent 196 (compound 6b) is a coumarin derivative containing oxime ether structure, and shows antifungal activity, with the EC50 of 0.46 μg/mL against Rhizoctonia solani .
    Antibacterial agent 196
  • HY-R04276
    rno-miR-196b-3p mimic

    		MicroRNA Cancer
    rno-miR-196b-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    rno-miR-196b-3p mimic
    rno-miR-196b-3p mimic
  • HY-RI00391
    hsa-miR-196b-5p inhibitor

    		MicroRNA Cancer
    hsa-miR-196b-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-196b-5p inhibitor
    hsa-miR-196b-5p inhibitor
  • HY-17600A
    Acalabrutinib maleate

    Calquence maleate; ACP-196 maleate

    		 Btk Cancer
    Acalabrutinib (Calquence) maleate is an orally active, irreversible, and highly selective second-generation BTK inhibitor. Acalabrutinib binds covalently to Cys481 in the ATP-binding pocket of BTK. Acalabrutinib maleate demonstrates potent on-target effects and efficacy in mouse models of chronic lymphocytic leukemia (CLL). Acalabrutinib maleate can be used for CLL research . Acalabrutinib maleate is a click chemistry reagent, which contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Acalabrutinib maleate
  • HY-RI00390A
    hsa-miR-196b-3p antagomir

    		MicroRNA Cancer
    hsa-miR-196b-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-196b-3p antagomir
    hsa-miR-196b-3p antagomir
  • HY-R04276A
    rno-miR-196b-3p agomir

    		MicroRNA Cancer
    rno-miR-196b-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    rno-miR-196b-3p agomir
    rno-miR-196b-3p agomir
  • HY-181479
    EGFR-IN-196

    		EGFR PI3K Akt Apoptosis Reactive Oxygen Species (ROS) Mitochondrial Metabolism Cancer
    EGFR-IN-196 is an EGFR inhibitor with an IC50 of 105.96 nM. EGFR-IN-196 inhibits EGFR enzymatic activity, reduces phosphorylated PI3K levels, and suppresses downstream EGFR-AKT signaling. EGFR-IN-196 increases intracellular ROS generation, induces mitochondrial depolarisation, and induces apoptosis in cancer cells. EGFR-IN-196 can be used for the research of lung cancer .
    EGFR-IN-196
  • HY-RI02791A
    mmu-miR-196a-1-3p antagomir

    		MicroRNA Cancer
    mmu-miR-196a-1-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-196a-1-3p antagomir
    mmu-miR-196a-1-3p antagomir
  • HY-RI04278A
    rno-miR-196c-5p antagomir

    		MicroRNA Cancer
    rno-miR-196c-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    rno-miR-196c-5p antagomir
    rno-miR-196c-5p antagomir
  • HY-RI02792A
    mmu-miR-196a-2-3p antagomir

    		MicroRNA Cancer
    mmu-miR-196a-2-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-196a-2-3p antagomir
    mmu-miR-196a-2-3p antagomir
  • HY-RI00390
    hsa-miR-196b-3p inhibitor

    		MicroRNA Cancer
    hsa-miR-196b-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-196b-3p inhibitor
    hsa-miR-196b-3p inhibitor
  • HY-100201R
    A-196 (Standard)

    		Histone Methyltransferase Reference Standards Cancer
    A-196 (Standard) is the analytical standard of A-196 (HY-100201). This product is intended for research and analytical applications. A-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively. A-196 inhibits SUV4-20 biochemically in a substrate-competitive manner. A-196 represents a first-in-class chemical probe of SUV4-20 to investigate the role of histone methyltransferases in genomic integrity .
    A-196 (Standard)
  • HY-R00390
    hsa-miR-196b-3p mimic

    		MicroRNA Cancer
    hsa-miR-196b-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-196b-3p mimic
    hsa-miR-196b-3p mimic
  • HY-RI00388
    hsa-miR-196a-3p inhibitor

    		MicroRNA Cancer
    hsa-miR-196a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-196a-3p inhibitor
    hsa-miR-196a-3p inhibitor
  • HY-RI00387A
    hsa-miR-196a-1-3p antagomir

    		MicroRNA Cancer
    hsa-miR-196a-1-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-196a-1-3p antagomir
    hsa-miR-196a-1-3p antagomir
  • HY-R02791A
    mmu-miR-196a-1-3p agomir

    		MicroRNA Cancer
    mmu-miR-196a-1-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-196a-1-3p agomir
    mmu-miR-196a-1-3p agomir
  • HY-R02791
    mmu-miR-196a-1-3p mimic

    		MicroRNA Cancer
    mmu-miR-196a-1-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-196a-1-3p mimic
    mmu-miR-196a-1-3p mimic
  • HY-RI00389A
    hsa-miR-196a-5p antagomir

    		MicroRNA Cancer
    hsa-miR-196a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-196a-5p antagomir
    hsa-miR-196a-5p antagomir

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