1874276-76-2
Chemical Structure
Darovasertib
Synonym(s): LXS196; IDE196
- CAS No.: 1874276-76-2
- Formula:C22H23F3N8O
- Molecular Weight:472.47
IUPAC Name: 3-amino-N-(3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl)-6-(3-(trifluoromethyl)pyridin-2-yl)pyrazine-2-carboxamide
InChIKey: XXJXHXJWQSCNPX-UHFFFAOYSA-N
SMILES: NC1=C(C(NC2=C(N3CCC(C)(N)CC3)C=CC=N2)=O)N=C(C4=NC=CC=C4C(F)(F)F)C=N1
Biological Activity: Darovasertib (LXS196) is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. Darovasertib has the potential for uveal melanoma research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Darovasertib | 99.78% | Darovasertib (LXS196) is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. Darovasertib has the potential for uveal melanoma research. | ||||||||||||||||||||
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Keywords
