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Acetylcholine chloride (Standard)

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19

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100806R
    Kynurenic acid (Standard)
    5+ Cited Publications

    Quinurenic acid (Standard)

    		 Reference Standards iGluR Endogenous Metabolite Apoptosis CXCR GPR35 Neurological Disease Inflammation/Immunology Endocrinology
    Kynurenic acid (Standard) is the analytical standard of Kynurenic acid. This product is intended for research and analytical applications. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8.
    Kynurenic acid (Standard)
  • HY-B0282R
    Acetylcholine chloride (Standard)

    ACh chloride (Standard)

    		 Reference Standards nAChR Calcium Channel Endogenous Metabolite Neurological Disease Cancer
    Acetylcholine (chloride) (Standard) is the analytical standard of Acetylcholine (chloride). This product is intended for research and analytical applications. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent and BBB-permeable cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs) . Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro .
    Acetylcholine chloride (Standard)
  • HY-14774R
    Monepantel (Standard)

    AAD1566 (Standard); NUZ-001 (Standard)

    		 Reference Standards nAChR Cancer
    Monepantel (Standard) is the analytical standard of Monepantel. This product is intended for research and analytical applications. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.
    Monepantel (Standard)
  • HY-B0942R
    Benzethonium chloride (Standard)

    		Reference Standards nAChR Bacterial Neurological Disease
    Benzethonium (chloride) (Standard) is the analytical standard of Benzethonium (chloride). This product is intended for research and analytical applications. Benzethonium chloride inhibits nicotinic acetylcholine receptors in human recombinant α7 and α4β2 neurons in Xenopus laevis oocytes.
    Benzethonium chloride (Standard)
  • HY-12640R
    Pyrantel pamoate (Standard)

    Pyrantel embonate (Standard)

    		 Reference Standards Parasite nAChR Antibiotic Infection
    Pyrantel (pamoate) (Standard) is the analytical standard of Pyrantel (pamoate). This product is intended for research and analytical applications. Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .
    Pyrantel pamoate (Standard)
  • HY-B1205R
    Atropine (Standard)

    Tropine tropate (Standard); DL-Hyoscyamine (Standard)

    		 Reference Standards mAChR Endogenous Metabolite Cardiovascular Disease Neurological Disease
    Atropine (Standard) is the analytical standard of Atropine. This product is intended for research and analytical applications. Atropine (Tropine tropate) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia .
    Atropine (Standard)
  • HY-B1315R
    Carbaryl (Standard)

    		Reference Standards Insecticide Cholinesterase (ChE) Reactive Oxygen Species (ROS) Apoptosis Neurological Disease Inflammation/Immunology
    Carbaryl (Standard) is the analytical standard of Carbaryl (HY-B1315). This product is intended for research and analytical applications. Carbaryl is the inhibitor for acetylcholinesterase that inhibits the degradation of acetylcholine in the synaptic cleft, leads to the accumulation of acetylcholine and causes neurotoxicity. Carbaryl can be used as an insecticide.
    Carbaryl (Standard)
  • HY-101036R
    Choline bitartrate (Standard)

    		Reference Standards mAChR Endogenous Metabolite Neurological Disease Cancer
    Choline (bitartrate) (Standard) is the analytical standard of Choline (bitartrate). This product is intended for research and analytical applications. Choline bitartrate is a vitamin-like essential nutrient, can affect diseases such as liver disease, atherosclerosis and neurological disorders . Choline bitartrate is a precursor for the neurotransmitter acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism .
    Choline bitartrate (Standard)
  • HY-B1205AR
    Atropine sulfate (Standard)

    Tropine tropate sulfate (Standard); DL-Hyoscyamine sulfate (Standard); Sulfatropinol (Standard)

    		 Reference Standards mAChR Cardiovascular Disease Neurological Disease
    Atropine (sulfate) (Standard) is the analytical standard of Atropine (sulfate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .
    Atropine sulfate (Standard)
  • HY-B0726R
    Pilocarpine Hydrochloride (Standard)

    		Reference Standards mAChR Neurological Disease Cancer
    Pilocarpine (Hydrochloride) (Standard) is the analytical standard of Pilocarpine (Hydrochloride). This product is intended for research and analytical applications. Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
    Pilocarpine Hydrochloride (Standard)
  • HY-B0823R
    Acetamiprid (Standard)

    		Reference Standards nAChR Neurological Disease
    Acetamiprid (Standard) is the analytical standard of Acetamiprid. This product is intended for research and analytical applications. Acetamiprid is a neonicotinoid insecticide used worldwide. Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist, and is shown to be associated with neuromuscular and reproductive disorders .
    Acetamiprid (Standard)
  • HY-13204R
    Biperiden hydrochloride (Standard)

    KL 373 hydrochloride (Standard)

    		 Reference Standards mAChR Neurological Disease
    Biperiden (hydrochloride) (Standard) is the analytical standard of Biperiden (hydrochloride). This product is intended for research and analytical applications. Biperiden (KL 373) hydrochloride is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system. Biperiden hydrochloride has the potential for the research of Parkinson's disease and other related psychiatric disorders .
    Biperiden hydrochloride (Standard)
  • HY-B0489R
    Arecoline hydrobromide (Standard)

    methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide (Standard)

    		 Reference Standards mAChR nAChR Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Arecoline hydrobromide (Standard) is the analytical standard of Arecoline hydrobromide. This product is intended for research and analytical applications. Arecoline hydrobromide, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .
    Arecoline hydrobromide (Standard)
  • HY-B2202R
    Choline dihydrogen citrate (Standard)

    		Biochemical Assay Reagents Reference Standards Others
    Choline dihydrogen citrate (Standard) is the analytical standard of Choline dihydrogen citrate. This product is intended for research and analytical applications. Choline dihydrogen citrate is a choline-rich hydrochloride that can be absorbed by the body and converted into acetylcholine, which enhances the function of the nervous system and muscles and promotes good health. In addition, this compound is widely used in supplements such as certain energy drinks and protein powders to help improve the body's metabolism and exercise capacity.
    Choline dihydrogen citrate (Standard)
  • HY-101086R
    Acetylcholine iodide (Standard)

    ACh iodide (Standard)

    		 Reference Standards Endogenous Metabolite mAChR Neurological Disease Endocrinology
    Acetylcholine (iodide) (Standard) is the analytical standard of Acetylcholine (iodide). This product is intended for research and analytical applications. Acetylcholine iodide (ACh iodide) is a common neurotransmitter found in the central and peripheral nerve system .
    Acetylcholine iodide (Standard)
  • HY-B1343R
    Pridinol mesylate (Standard)

    		Reference Standards Cholinesterase (ChE) Neurological Disease
    Pridinol mesylate (Standard) is the analytical standard of Pridinol mesylate (HY-B1343). This product is intended for research and analytical applications. Pridinol mesylate is an orally active, blood-brain permeable, muscarinic acetylcholine receptor (mAChR)-directed muscle relaxant. Pridinol mesylate reduces the conduction of impulses to spinal motor neurons and exerts muscle relaxant activity. Pridinol mesylate inhibits skeletal muscle contractures in diseases of both central and peripheral origin and can be used in research in the field of musculoskeletal diseases .
    Pridinol mesylate (Standard)
  • HY-A0083R
    Methacholine chloride (Standard)

    Acetyl-β-methylcholine chloride (Standard)

    		 Reference Standards mAChR Others
    Methacholine (chloride) (Standard) is the analytical standard of Methacholine (chloride). This product is intended for research and analytical applications. Methacholine (Acetyl-β-methylcholine) choride is a potent muscarinic-3 (M3) agonist. Methacholine choride acts directly on acetylcholine receptors on smooth muscle causing bronchoconstriction and airway narrowing. Methacholine choride shows a high sensitivity to identify bronchial hyperresponsiveness (BHR). Methacholine choride can be used to measure airway hyperresponsiveness (AHR) as a diagnostic aid in the assessment of individuals with asthma-like symptoms and normal resting expiratory flow rates .
    Methacholine chloride (Standard)
  • HY-10021R
    Varenicline Tartrate (Standard)

    CP 526555-18 (Standard)

    		 Reference Standards nAChR ERK p38 MAPK Others Neurological Disease
    Varenicline (Tartrate) (Standard) is the analytical standard of Varenicline (Tartrate). This product is intended for research and analytical applications. Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation .
    Varenicline Tartrate (Standard)
  • HY-N0443R
    N-Methylcytisine (Standard)

    Caulophylline (Standard)

    		 Reference Standards nAChR Inflammation/Immunology
    N-Methylcytisine (Standard) is the analytical standard of N-Methylcytisine. This product is intended for research and analytical applications. N-Methylcytisine (Caulophylline), a tricyclic quinolizidine alkaloid, exerts hypoglycaemic, analgesic and anti-inflammatory activities. N-methylcytisine is a selective ligand of nicotinic receptors of acetylcholine in the central nervous system and has a high affinity (Kd = 50 nM) to nicotinic acetylcholine receptors (nAChR) from squid optical ganglia .
    N-Methylcytisine (Standard)
  • HY-B0547AR
    Homatropine Bromide (Standard)

    		Reference Standards mAChR Neurological Disease
    Homatropine (Bromide) (Standard) is the analytical standard of Homatropine (Bromide). This product is intended for research and analytical applications. Homatropine Bromide is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent .
    Homatropine Bromide (Standard)
  • HY-145297R
    Flupyrimin (Standard)

    		Reference Standards nAChR Insecticide Neurological Disease
    Flupyrimin (Standard) is the analytical standard of Flupyrimin. This product is intended for research and analytical applications. Flupyrimin is the antagonist for insect nicotinic acetylcholine receptor (nAChR) that exhibits insecticidal effect by targeting insect nervous system .
    Flupyrimin (Standard)
  • HY-13596R
    Cisatracurium besylate (Standard)

    51W89 besylate (Standard); Cisatracurium besilate (Standard)

    		 Reference Standards nAChR Autophagy Neurological Disease Cancer
    Cisatracurium (besylate) (Standard) is the analytical standard of Cisatracurium (besylate). This product is intended for research and analytical applications. Cisatracurium besylate (51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.
    Cisatracurium besylate (Standard)
  • HY-B1006R
    Pilocarpine nitrate (Standard)

    		Reference Standards mAChR Neurological Disease Cancer
    Pilocarpine (nitrate) (Standard) is the analytical standard of Pilocarpine (nitrate). This product is intended for research and analytical applications. Pilocarpine nitrate is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
    Pilocarpine nitrate (Standard)
  • HY-B0106AR
    Etiracetam (Standard)

    UCB 6474 (Standard)

    		 Reference Standards Calcium Channel Neurological Disease
    Etiracetam (Standard) is the analytical standard of Etiracetam. This product is intended for research and analytical applications. Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059) .
    Etiracetam (Standard)
  • HY-100196AR
    Pyrroloquinoline quinone disodium salt (Standard)

    PQQ disodium salt (Standard); Methoxatin disodium salt (Standard)

    		 Reference Standards Endogenous Metabolite Inflammation/Immunology
    Triazophos (Standard) is the analytical standard of Triazophos. This product is intended for research and analytical applications. Triazophos, a non-systemic insecticide and acaricide that acts as an acetylcholinesterase (AChE) inhibitor, covalently and irreversibly binds to the acetylcholine binding site, thus blocking the hydrolysis of acetylcholine and leading to hyperexcitability; it is effective against a variety of soil insects and mites, including aphids, thrips, midges, beetles, Lepidoptera larvae, cutworms, and spider mites in crops such as ornamentals, cotton, rice, maize, soybeans, oil palms, olives, and coffee.
    Pyrroloquinoline quinone disodium salt (Standard)
  • HY-B0828R
    Triazophos (Standard)

    		Parasite Reference Standards Others
    Triazophos (Standard) is the analytical standard of Triazophos. This product is intended for research and analytical applications. Triazophos, a non-systemic insecticide and acaricide that acts as an acetylcholinesterase (AChE) inhibitor, covalently and irreversibly binds to the acetylcholine binding site, thus blocking the hydrolysis of acetylcholine and leading to hyperexcitability; it is effective against a variety of soil insects and mites, including aphids, thrips, midges, beetles, Lepidoptera larvae, cutworms, and spider mites in crops such as ornamentals, cotton, rice, maize, soybeans, oil palms, olives, and coffee.
    Triazophos (Standard)
  • HY-B0820R
    Nitenpyram (Standard)

    		Reference Standards nAChR Parasite Neurological Disease
    Nitenpyram (Standard) is the analytical standard of Nitenpyram. This product is intended for research and analytical applications. Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals .
    Nitenpyram (Standard)
  • HY-B0321R
    Tropicamide (Standard)

    Ro 1-7683 (Standard)

    		 Reference Standards mAChR Neurological Disease
    Tropicamide (Standard) is the analytical standard of Tropicamide. This product is intended for research and analytical applications. Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist. Tropicamide produces short acting mydriasis (dilation of the pupil) and cycloplegia when applied as eye drops .
    Tropicamide (Standard)
  • HY-107512R
    Kynurenic acid sodium (Standard)

    		iGluR Apoptosis Endogenous Metabolite CXCR GPR35 Reference Standards Neurological Disease Inflammation/Immunology Endocrinology
    Kynurenic acid (sodium) (Standard) is the analytical standard of Kynurenic acid (sodium). This product is intended for research and analytical applications. Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8.
    Kynurenic acid sodium (Standard)
  • HY-N7247R
    Thiochrome (Standard)

    		Reference Standards mAChR Metabolic Disease
    Thiochrome (Standard) is the analytical standard of Thiochrome. This product is intended for research and analytical applications. Thiochrome, a natural oxidation product and metabolite of thiamine, is a selective M4 muscarinic receptor of acetylcholine (ACh) affinity enhancer. Thiochrome has neutral cooperativity with ACh at M1 to M3 receptors .
    Thiochrome (Standard)
  • HY-B0118AR
    Vecuronium bromide (Standard)

    ORG NC 45 (Standard)

    		 Reference Standards nAChR Neurological Disease Cancer
    Vecuronium (bromide) (Standard) is the analytical standard of Vecuronium (bromide). This product is intended for research and analytical applications. Vecuronium (ORG NC 45) bromide is a non-depolarizing neuromuscular blocking agent that also acts as a nicotinic acetylcholine receptor (nAChR) inhibitor, a muscle relaxant, and can be used for pre-surgical anesthesia .
    Vecuronium bromide (Standard)
  • HY-100651R
    Desmethylnortriptyline (Standard)

    		Reference Standards Drug Metabolite Neurological Disease
    Desmethylnortriptyline (Standard) is the analytical standard of Desmethylnortriptyline (HY-100651). This product is intended for research and analytical applications. Desmethylnortriptyline is a metabolite of Amitriptyline (HY-B0527) and Nortriptyline (HY-118620). Desmethylnortriptylineinhibits serotonin and noradrenaline uptake, antagonizes acetylcholine-induced contraction. Desmethylnortriptyline can be used for the research of depression .
    Desmethylnortriptyline (Standard)
  • HY-17460AR
    Garenoxacin Mesylate hydrate (Standard)

    BMS284756 Mesylate hydrate (Standard)

    		 Reference Standards Bacterial Topoisomerase DNA/RNA Synthesis Antibiotic Infection
    ACHE-IN-38 (hydrochloride) (Standard) is the analytical standard of ACHE-IN-38 (hydrochloride). This product is intended for research and analytical applications. ACHE-IN-38 hydrochloride (Compound 13b) inhibits the metabolic breakdown of the neurotransmitter acetylcholine (ACh) by the enzyme acetylcholinesterase (AChE) and hence alleviates memory deficits in patients with Alzheimer’s Disease by potentiating cholinergic transmission .
    Garenoxacin Mesylate hydrate (Standard)
  • HY-103182R
    PSB-1115 (Standard)

    		Reference Standards Adenosine Receptor Others
    PSB-1115 (Standard) is the analytical standard of PSB-1115. This product is intended for research and analytical applications. PSB-1115 is a selective A2B Adenosine Receptor antagonist. PSB-1115 inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh) .
    PSB-1115 (Standard)
  • HY-W003576R
    ACHE-IN-38 hydrochloride (Standard)

    		Cholinesterase (ChE) Reference Standards Neurological Disease
    ACHE-IN-38 (hydrochloride) (Standard) is the analytical standard of ACHE-IN-38 (hydrochloride). This product is intended for research and analytical applications. ACHE-IN-38 hydrochloride (Compound 13b) inhibits the metabolic breakdown of the neurotransmitter acetylcholine (ACh) by the enzyme acetylcholinesterase (AChE) and hence alleviates memory deficits in patients with Alzheimer’s Disease by potentiating cholinergic transmission .
    ACHE-IN-38 hydrochloride (Standard)
  • HY-B1700AR
    Mivacurium dichloride (Standard)

    		Reference Standards nAChR Neurological Disease
    Mivacurium (dichloride) (Standard) is the analytical standard of Mivacurium (dichloride). This product is intended for research and analytical applications. Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell .
    Mivacurium dichloride (Standard)
  • HY-B0429R
    Pancuronium dibromide (Standard)

    		Reference Standards nAChR Neurological Disease
    Pancuronium (dibromide) (Standard) is the analytical standard of Pancuronium (dibromide). This product is intended for research and analytical applications. Pancuronium dibromide, a bis-quaternary steroid, is a neuromuscular relaxant. Pancuronium dibromide inhibits neuromuscular transmission by competing with acetylcholine for binding sites on nACh receptors. Pancuronium dibromide also inhibits cardiac muscarinic receptors and has a sympathomimetic action .
    Pancuronium dibromide (Standard)
  • HY-17037R
    Pirenzepine dihydrochloride (Standard)

    LS 519 (Standard); Pirenzepin dihydrochloride (Standard); Gastrozepin dihydrochloride (Standard)

    		 Reference Standards mAChR Metabolic Disease Cancer
    Pirenzepine (dihydrochloride) (Standard) is the analytical standard of Pirenzepine (dihydrochloride). This product is intended for research and analytical applications. Pirenzepine (LS 519) dihydrochloride is a selective M1 mAChR (muscarinic acetylcholine receptor) antagonist. Pirenzepine dihydrochloride reduces gastric acid secretion and reduces muscle spasm, can be used in peptic ulcers research. Pirenzepine dihydrochloride shows anti-proliferative activity to cancer cells .
    Pirenzepine dihydrochloride (Standard)
  • HY-17037AR
    Pirenzepine (Standard)

    LS 519 free base (Standard); Pirenzepin (Standard); Gastrozepin (Standard)

    		 mAChR Reference Standards Metabolic Disease Cancer
    Pirenzepine (Standard) is the analytical standard of Pirenzepine. This product is intended for research and analytical applications. Pirenzepine (LS 519 free base) is a selective M1 mAChR (muscarinic acetylcholine receptor) antagonist. Pirenzepine reduces gastric acid secretion and reduces muscle spasm, can be used in peptic ulcers research. Pirenzepine shows anti-proliferative activity to cancer cells .
    Pirenzepine (Standard)
  • HY-W011235R
    Norfluoxetine hydrochloride (Standard)

    		Reference Standards 5-HT Receptor Calcium Channel Drug Metabolite Cardiovascular Disease Neurological Disease
    Arecoline (hydrobromide) (Standard) is the analytical standard of Arecoline (hydrobromide). This product is intended for research and analytical applications. Arecoline hydrobromide, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .
    Norfluoxetine hydrochloride (Standard)
  • HY-13204AR
    Biperiden (Standard)

    KL 373 (Standard)

    		 Reference Standards mAChR Neurological Disease
    Biperiden (Standard) is the analytical standard of Biperiden. This product is intended for research and analytical applications. Biperiden (KL 373) is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system. Biperiden has the potential for the research of Parkinson's disease and other related psychiatric disorders .
    Biperiden (Standard)
  • HY-111338R
    Tacrine (Standard)

    		Cholinesterase (ChE) Reference Standards Neurological Disease
    Tacrine (Standard) is the analytical standard of Tacrine. This product is intended for research and analytical applications. Tacrine is an effective oral acetylcholine (AChE) inhibitor (IC50 = 109 nM) and also acts as an active substrate for CYP1A2. Tacrine can restore cognitive dysfunction in elderly rats. Tacrine can cause liver toxicity and is used in research related to Alzheimer's disease .
    Tacrine (Standard)
  • HY-W278867R
    trans-3,5-Dimethoxystilbene (Standard)

    trans-Pinosylvin dimethyl ether (Standard)

    		 Reference Standards Cholinesterase (ChE) Neurological Disease
    trans-3,5-Dimethoxystilbene (Standard) is the analytical standard of trans-3,5-Dimethoxystilbene (HY-W278867). This product is intended for research and analytical applications. trans-3,5-Dimethoxystilbene (trans-Pinosylvin dimethyl ether) is a natural stilbenoid metabolite. trans-3,5-Dimethoxystilbene acts as an acetylcholinesterase inhibitor with a IC50 of 9 μM against Electrophorus electricus acetylcholinesterase. trans-3,5-Dimethoxystilbene binds to acetylcholinesterase and blocks acetylcholine hydrolysis, thereby increasing acetylcholine levels in the cholinergic synaptic cleft. trans-,5-Dimethoxystilbene can be used in the research of neurodegenerative diseases such as Alzheimer's disease .
    trans-3,5-Dimethoxystilbene (Standard)
  • HY-12641R
    Pyrantel tartrate (Standard)

    		Reference Standards Parasite nAChR Antibiotic Infection
    Pyrantel (tartrate) (Standard) is the analytical standard of Pyrantel (tartrate). This product is intended for research and analytical applications. Pyrantel tartrate is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel tartrate can cause spasmodic muscle paralysis in parasites. Pyrantel tartrate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .
    Pyrantel tartrate (Standard)
  • HY-B0732R
    Itopride hydrochloride (Standard)

    HSR803 (Standard)

    		 Reference Standards Cholinesterase (ChE) Dopamine Receptor Bacterial Neurological Disease
    Itopride (hydrochloride) (Standard) is the analytical standard of Itopride (hydrochloride). This product is intended for research and analytical applications. Itopride (HSR803) hydrochloride is a potent dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. Itopride hydrochloride enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, can be used as a gastrointestinal prokinetic agent. Itopride can be used for researching gastro-esophageal reflux disease (GERD) .
    Itopride hydrochloride (Standard)
  • HY-70020BR
    Cevimeline hydrochloride (Standard)

    AF102B hydrochloride (Standard)

    		 mAChR Reference Standards Neurological Disease Cancer
    Cevimeline (hydrochloride) (Standard) is the analytical standard of Cevimeline (hydrochloride). This product is intended for research and analytical applications. Cevimeline hydrochloride (AF102B hydrochloride) is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist. Cevimeline hydrochloride stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia . Cevimeline hydrochloride can cross the blood-brain barrier (BBB) .
    Cevimeline hydrochloride (Standard)
  • HY-B1532R
    Anabasine (Standard)

    (S)-Anabasine (Standard); (+)-Anabasine (Standard)

    		 Reference Standards nAChR Neurological Disease
    Anabasine (Standard) is the analytical standard of Anabasine. This product is intended for research and analytical applications. Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
    Anabasine (Standard)
  • HY-17360R
    Tiotropium Bromide (Standard)

    BA679 BR (Standard)

    		 Reference Standards mAChR Neurological Disease
    Tiotropium (Bromide) (Standard) is the analytical standard of Tiotropium (Bromide). This product is intended for research and analytical applications. Tiotropium bromide (BA-679 BR) is a long-acting anticholinergic bronchodilator. Tiotropium bromide blocks the action of acetylcholine at muscarinic M1, M2, and M3 receptors, prevents bronchoconstriction, and dilates bronchial airways. Tiotropium bromide is applicable to research related to chronic obstructive pulmonary disease and asthma .
    Tiotropium Bromide (Standard)
  • HY-112076R
    Atropine methyl bromide (Standard)

    Methylatropine bromide (Standard)

    		 Reference Standards mAChR Neurological Disease
    Atropine methyl bromide (Standard) is the analytical standard of Atropine methyl bromide. This product is intended for research and analytical applications. Atropine methyl bromide (Methylatropine bromide), an antagonist of muscarinic acetylcholine receptors (mAChR), is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine .
    Atropine methyl bromide (Standard)
  • HY-B0379AR
    Adiphenine hydrochloride (Standard)

    		Reference Standards nAChR Neurological Disease
    Adiphenine (hydrochloride) (Standard) is the analytical standard of Adiphenine (hydrochloride). This product is intended for research and analytical applications. Adiphenine hydrochloride is a non-competitive inhibitor of nicotinic acetylcholine receptor (nAChR), with an IC50s of 1.9, 1.8, 3.7, and 6.3 μM for α1, α3β4, α4β2, and α4β4, respectively. Adiphenine hydrochloride has anticonvulsant effects .
    Adiphenine hydrochloride (Standard)

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