1235-82-1
Chemical Structure
Biperiden hydrochloride
Synonym(s): KL 373 hydrochloride
- CAS No.: 1235-82-1
- Formula:C21H30ClNO
- Molecular Weight:347.92
IUPAC Name: 1-(bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride
InChIKey: RDNLAULGBSQZMP-UHFFFAOYSA-N
SMILES: OC(C1CC2C=CC1C2)(CCN3CCCCC3)C4=CC=CC=C4.[H]Cl
Biological Activity: Biperiden (KL 373) hydrochloride is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system. Biperiden hydrochloride has the potential for the research of Parkinson's disease and other related psychiatric disorders[1][2].
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Biperiden hydrochloride | 99.90% | Biperiden (KL 373) hydrochloride is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system. Biperiden hydrochloride has the potential for the research of Parkinson's disease and other related psychiatric disorders. | ||||||||||||||||||||
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Biperiden hydrochloride (Standard) | ≥98% | Biperiden (hydrochloride) (Standard) is the analytical standard of Biperiden (hydrochloride). This product is intended for research and analytical applications. Biperiden (KL 373) hydrochloride is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system. Biperiden hydrochloride has the potential for the research of Parkinson's disease and other related psychiatric disorders. | ||||||||||||||||||||
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rel-Biperiden EP impurity A-d5 | rel-Biperiden EP impurity A-d5 is deuterium labeled Biperiden (hydrochloride). | |||||||||||||||||||||
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rel-Biperiden EP impurity B-d5 | rel-Biperiden EP impurity B-d5 is deuterium labeled Biperiden (hydrochloride). | |||||||||||||||||||||
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Biperiden-d5 hydrochloride | Biperiden-d5 (hydrochloride) is the deuterium labeled Biperiden hydrochloride. Biperiden (KL 373) hydrochloride is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. | |||||||||||||||||||||
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rel-Biperiden-d5 | rel-Biperiden-d5 is deuterium labeled Biperiden (hydrochloride). | |||||||||||||||||||||
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- [1]. Leonie Konczalla，et al. Biperiden and mepazine effectively inhibit MALT1 activity and tumor growth in pancreatic cancer. Int J Cancer. 2020 Mar 15;146(6):1618-1630. [Content Brief]
- [2]. Simone Bittencourt, et al. Modification of the natural progression of epileptogenesis by means of biperiden in the pilocarpine model of epilepsy. Epilepsy Res. 2017 Dec;138:88-97. doi: 10.1016/j.eplepsyres.2017.10.019. Epub 2017 Oct 29. [Content Brief]
