22204-24-6
22204-24-6
Chemical Structure
Pyrantel pamoate
Synonym(s): Pyrantel embonate
- CAS No.: 22204-24-6
- Formula:C34H30N2O6S
- Molecular Weight:594.68
IUPAC Name: (E)-1-methyl-2-(2-(thiophen-2-yl)vinyl)-1,4,5,6-tetrahydropyrimidine 4,4'-methylenebis(3-hydroxy-2-naphthoate)
InChIKey: AQXXZDYPVDOQEE-MXDQRGINSA-N
SMILES: O=C(C1=C(O)C(CC2=C3C=CC=CC3=CC(C(O)=O)=C2O)=C4C=CC=CC4=C1)O.CN5CCCN=C5/C=C/C6=CC=CS6
Biological Activity: Pyrantel pamoate is an orally active antiparasitic agent. Pyrantel pamoate induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel pamoate eliminates both immature and mature endoparasites in horses. Pyrantel pamoate can be used in research related to parasitic infections[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pyrantel pamoate | 99.97% | Pyrantel pamoate is an orally active antiparasitic agent. Pyrantel pamoate induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel pamoate eliminates both immature and mature endoparasites in horses. Pyrantel pamoate can be used in research related to parasitic infections. | ||||||||||||||||||||
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Pyrantel pamoate (Standard) | 97.20% | Pyrantel pamoate (Standard) (Pyrantel embonate (Standard)) is the analytical standard of Pyrantel pamoate (HY-12640). This product is intended for research and analytical applications. Pyrantel pamoate is an orally active antiparasitic agent. Pyrantel pamoate induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel pamoate eliminates both immature and mature endoparasites in horses. Pyrantel pamoate can be used in research related to parasitic infections. | ||||||||||||||||||||
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Pyrantel-d10 pamoate | Pyrantel-d10 pamoate (Pyrantel embonate-d10) is the deuterated-labeled Pyrantel pamoate (HY-12640). Pyrantel pamoate is an orally active antiparasitic agent. Pyrantel pamoate induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel pamoate eliminates both immature and mature endoparasites in horses. Pyrantel pamoate can be used in research related to parasitic infections. | |||||||||||||||||||||
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Pyrantel-d5 pamoate | Pyrantel-d5 pamoate (Pyrantel embonate-d5) is the deuterated-labeled Pyrantel pamoate (HY-12640). Pyrantel pamoate is an orally active antiparasitic agent. Pyrantel pamoate induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel pamoate eliminates both immature and mature endoparasites in horses. Pyrantel pamoate can be used in research related to parasitic infections. | |||||||||||||||||||||
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Pyrantel-d3 pamoate | Pyrantel-d3 pamoate (Pyrantel embonate-d3) is the deuterated-labeled Pyrantel pamoate (HY-12640). Pyrantel pamoate is an orally active antiparasitic agent. Pyrantel pamoate induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel pamoate eliminates both immature and mature endoparasites in horses. Pyrantel pamoate can be used in research related to parasitic infections. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.85
HY-B1344ROxantel pamoate (Standard) -
Similarity Score 0.69
HY-W008613Pamoic acid -
Similarity Score 0.61
HY-W010907Pamoic acid disodium -
Similarity Score 0.59
HY-B0895RHydroxyzine pamoate (Standard) -
Similarity Score 0.52
HY-W008613AAmitriptyline pamoate -
Similarity Score 0.51
HY-107956Imipramine pamoate -
Similarity Score 0.50
HY-W1130174,4'-(Anthracene-9,10-diyl)bis(2-hydroxybenzoicacid) -
Similarity Score 0.49
HY-12641RPyrantel tartrate (Standard) -
Similarity Score 0.48
HY-Z12310Salmeterol impurity 7 -
Explore the MedChemAI to find more analogs
References
- [1]. Tritten L, et al. In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections. PLoS neglected tropical diseases. 2011 Dec;5(12):e1457. [Content Brief]
- [2]. Martin RJ, et al. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. International journal for parasitology. 2004 Aug;34(9):1083-90. [Content Brief]
- [3]. Lyons ET, et al. Critical test of three salts of pyrantel against internal parasites of the horse. Am J Vet Res. 1974 Dec;35(12):1515-22. [Content Brief]
