1. MAPK/ERK Pathway
    Stem Cell/Wnt
  2. ERK
  3. Pamoic acid disodium

Pamoic acid disodium 

Cat. No.: HY-W010907
Handling Instructions

Pamoic acid disodium is a potent GPR35 agonist with an EC50 value of 79 nM. Pamoic acid disodium induces GPR35 internalization and activates ERK1/2 with EC50 values of 22 nM and 65 nM, respectively. Pamoic acid disodium potently recruits β-arrestin2 to GPR35 and has an antinociceptive effect.

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Pamoic acid disodium Chemical Structure

Pamoic acid disodium Chemical Structure

CAS No. : 6640-22-8

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Description

Pamoic acid disodium is a potent GPR35 agonist with an EC50 value of 79 nM. Pamoic acid disodium induces GPR35 internalization and activates ERK1/2 with EC50 values of 22 nM and 65 nM, respectively. Pamoic acid disodium potently recruits β-arrestin2 to GPR35 and has an antinociceptive effect[1].

IC50 & Target

EC50: 79 nM (GPR35), 65 nM (ERK1/2)[1]

Molecular Weight

432.33

Formula

C₂₃H₁₄Na₂O₆

CAS No.

6640-22-8

SMILES

OC1=C(C(C=CC=C2)=C2C=C1C(O[Na])=O)CC(C(C=CC=C3)=C3C=C4C(O[Na])=O)=C4O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Pamoic acid disodiumERKExtracellular signal regulated kinasesGPR35inactiveβ-arrestin2ERK1ERK2antinociceptiveInhibitorinhibitorinhibit

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Pamoic acid disodium
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HY-W010907
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