6640-22-8
6640-22-8
Chemical Structure
Pamoic acid disodium
- CAS No.: 6640-22-8
- Formula:C23H14Na2O6
- Molecular Weight:432.33
IUPAC Name: sodium 4,4'-methylenebis(3-hydroxy-2-naphthoate)
InChIKey: YGLLICRFEVEWOZ-UHFFFAOYSA-L
SMILES: OC1=C(C(C=CC=C2)=C2C=C1C(O[Na])=O)CC(C(C=CC=C3)=C3C=C4C(O[Na])=O)=C4O
Biological Activity: Pamoic acid disodium is a potent GPR35 agonist with an EC50 value of 79 nM. Pamoic acid disodium induces GPR35 internalization and activates ERK1/2 with EC50 values of 22 nM and 65 nM, respectively. Pamoic acid disodium potently recruits β-arrestin2 to GPR35 and has an antinociceptive effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pamoic acid disodium | 99.86% | Pamoic acid disodium is a potent GPR35 agonist with an EC50 value of 79 nM. Pamoic acid disodium induces GPR35 internalization and activates ERK1/2 with EC50 values of 22 nM and 65 nM, respectively. Pamoic acid disodium potently recruits β-arrestin2 to GPR35 and has an antinociceptive effect. | ||||||||||||||||||||
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References
Keywords
