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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Agomelatine hydrochloride
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Agomelatine hydrochloride" in MCE Product Catalog:
9
9 Publications Verification
Cat. No.: HY-17038A
CAS No.: 1176316-99-6
Synonyms: S-20098 hydrochloride
Target:
Research Areas:
Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively . Agomelatine hydrochloride is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively .
9
Category:
Target:
9
9 Publications Verification
Cat. No.: HY-17038B
CAS No.: 824393-18-2
Synonyms: S-20098 L(+)-Tartaric acid
1
1 Cited Publications
Target:
Research Areas:
7-Desmethyl-agomelatine is a metabolite of Agomelatine. Agomelatineis a potent agonist at melatonin receptors (MT1 and MT2), and also is an antagonist of 5-HT2C .
Cat. No.: HY-17038S
CAS No.: 1079389-42-6
Synonyms: S-20098-d6
Cat. No.: HY-17038S2
CAS No.: 1079389-38-0
Synonyms: S-20098-d3
Target:
Research Areas:
3-Hydroxy agomelatine is a metabolite of Agomelatine. 3-Hydroxy agomelatine is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM .
Cat. No.: HY-17038R
CAS No.: 138112-76-2
Synonyms: S-20098 (Standard)
Category:
Cat. No.: HY-17038S1
CAS No.: 1079389-44-8
Synonyms: S-20098-d4
Cat. No.: HY-133112
CAS No.: 166527-00-0
Synonyms: 3-Hydroxy-7-desmethyl Agomelatine
Target:
Research Areas:
7-Desmethyl-3-hydroxyagomelatine (3-Hydroxy-7-desmethyl agomelatine), a metabolite of Agomelatine, has less activity than Agomelatine . Agomelatine is a melatonergic (MT1 and MT2) agonist and serotonergic (5HT2C) antagonist .
Cat. No.: HY-17038AR
CAS No.: 1176316-99-6
Synonyms: S-20098 hydrochloride (Standard)
Category:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
