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Aromatase-IN-1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136745
    Aromatase-IN-1

    		Cytochrome P450 Cancer
    Aromatase-IN-1 is a competitive aromatase (P450arom) inhibitor with a human IC50 of 40 nM and a Ki of 1.05 nM. Aromatase-IN-1 binds via coordination of imidazole nitrogen to the heme iron of aromatase. Aromatase-IN-1 can be used for the research of breast cancer [1].
    Aromatase-IN-1
  • HY-144824
    Monoamine oxidase/Aromatase-IN-1

    		Cytochrome P450 Monoamine Oxidase Neurological Disease Cancer
    Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a highly potent monoamine oxidase (MAO) and aromatase dual inhibitor with IC50s of 39 nM and 31 nM for MAO-B and aromatase, respectively. Monoamine oxidase/Aromatase-IN-1 can be used for researching neurological disorder and breast cancer [1].
    Monoamine oxidase/Aromatase-IN-1
  • HY-19599A
    (Rac)-Vorozole

    (Rac)-R83842

    		 Cytochrome P450 Drug Isomer Others
    (Rac)-Vorozole ((Rac)-R83842) is a racemate of Vorozole. Vorozole (HY-19599) is a potent and selective, orally active non-steroidal aromatase inhibitor .
    (Rac)-Vorozole
  • HY-19599
    Vorozole

    (+)-Vorozole; R83842

    		 Cytochrome P450 Cancer
    Vorozole is a potent and selective, orally active non-steroidal aromatase inhibitor . Vorozole shows antitumor activity in vivo. Vorozole has the potential for the research of mammary cancer .
    Vorozole
  • HY-181235
    COX-2/Aromatase-IN-1

    		COX Cytochrome P450 Inflammation/Immunology Cancer
    COX-2/Aromatase-IN-1 is a potent dual inhibitor of COX-2 and aromatase. COX-2/Aromatase-IN-1 can simultaneously inhibit COX-2 and aromatase, significantly suppress inflammation and induce proliferation inhibition of breast cancer cells. COX-2/Aromatase-IN-1 exerts anti-breast cancer and anti-inflammatory effects in the MCF-7 breast cancer cell and carrageenan-induced rat paw edema model. COX-2/Aromatase-IN-1 can be used for the study of inflammation and breast cancer [1].
    COX-2/Aromatase-IN-1

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