331684-05-0
331684-05-0
Chemical Structure
Aromatase-IN-1
- CAS No.: 331684-05-0
- Formula:C17H11N3O4
- Molecular Weight:321.29
IUPAC Name: 4-((1H-imidazol-1-yl)methyl)-1-nitro-9H-xanthen-9-one
InChIKey: JLTNBMDVMUSXHQ-UHFFFAOYSA-N
SMILES: O=C1C2=C(OC3=C1C([N+]([O-])=O)=CC=C3CN4C=NC=C4)C=CC=C2
Biological Activity: Aromatase-IN-1 is a competitive aromatase (P450arom) inhibitor with a human IC50 of 40 nM and a Ki of 1.05 nM. Aromatase-IN-1 binds via coordination of imidazole nitrogen to the heme iron of aromatase. Aromatase-IN-1 can be used for the research of breast cancer[1].
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Aromatase-IN-1 | Aromatase-IN-1 is a competitive aromatase (P450arom) inhibitor with a human IC50 of 40 nM and a Ki of 1.05 nM. Aromatase-IN-1 binds via coordination of imidazole nitrogen to the heme iron of aromatase. Aromatase-IN-1 can be used for the research of breast cancer. | |||||||||||||||||||||
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References
Keywords
