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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
BR-3
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "BR-3" in MCE Product Catalog:
Cat. No.: HY-P99487
CAS No.: 869881-54-9
Synonyms: BR 3FC
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Research Areas:
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Exatecan-amide-cyclopropanol (compound 1) is a anticancer agent. Exatecan-amide-cyclopropanol shows anti-proliferation activity against SK-BR-3 and U87 cells, with IC50 values of 0.12 and 0.23 nM, respectively .
Cat. No.: HY-W190881
CAS No.: 2098982-00-2
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N3-PEG11-CH2CH2Br is a PEG linker containing a bromine and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromine (Br) is a very good leaving group for nucleophilic substitution reactions.
Cat. No.: HY-10062
CAS No.: 345915-10-8
Synonyms: EBP-921
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AZD3409 is a prenyl inhibitor that exhibits inhibitory activity against both farnesyl transferase and geranylgeranyl transferase I. AZD3409 inhibits the growth of breast cancer cells, with IC50s of 220 nM (MDA-MB-468), 180 nM (MDA-MB-361), and 290 nM (SK-Br-3). AZD3409 significantly reduces the activation level of AKT in breast cancer cell lines. AZD3409 induces G0/G1 phase arrest in MDA-MB-468 cells, causes G2/M phase arrest in MDA-MB-361 cells. AZD3409 can be used for the study of breast cancer .
Cat. No.: HY-P992424
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Cat. No.: HY-N1265
CAS No.: 1207181-57-4
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Cat. No.: HY-173640
CAS No.: 2785317-21-5
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ID11916 is an orally active androgen receptor (AR) antagonist and a phosphodiesterase 5 (PDE5) inhibitor. ID11916 blocks androgen binding to AR, nuclear translocation, and androgen-dependent transcriptional activity of AR, while increasing intracellular cGMP levels and activating PKG via inhibition. ID11916 shows potent anti-cancer effect in prostate cancer cell lines VCaP and 22Rv1 and in AR-positive breast cancer cell lines SK-BR-3 .
Cat. No.: HY-P10393
CAS No.: 938077-77-1
Synonyms: ERα (295-311)
Cat. No.: HY-159519
EGFR/HER2-IN-16 (compound 12K) is an effective dual-target inhibitor of EGFR (IC50=6.15 nM) and HER-2 (IC50=9.78 nM) with anti-tumor activity. EGFR/HER2-IN-16 can inhibit the migration of SK-BR-3 cells, arrest the cell cycle in the G0/G1 phase, and induce apoptosis. EGFR/HER2-IN-16 exhibits good anti-proliferative activity against tumor cell models and has little damage to healthy cells. EGFR/HER2-IN-16 can be used in breast cancer research .
Cat. No.: HY-P703872
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF13C; BLyS Receptor 3; TNF Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor; BAFFR; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; Prolixin; CD268; BROMIX; Tumor Necrosis Factor Receptor Superfamily, Member
Cat. No.: HY-P703873
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF13C; BLyS Receptor 3; TNF Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor; BAFFR; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; Prolixin; CD268; BROMIX; Tumor Necrosis Factor Receptor Superfamily, Member
Cat. No.: HY-P704304
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF13C; BLyS Receptor 3; TNF Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor; BAFFR; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; Prolixin; CD268; BROMIX; Tumor Necrosis Factor Receptor Superfamily, Member
Cat. No.: HY-P76744
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF13C; BLyS Receptor 3; TNF Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor; BAFFR; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; Prolixin; CD268; BROMIX; Tumor Necrosis Factor Receptor Superfamily, Member
Cat. No.: HY-P700453
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF13C; BLyS Receptor 3; TNF Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor; BAFFR; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; Prolixin; CD268; BROMIX; Tumor Necrosis Factor Receptor Superfamily, Member
Cat. No.: HY-P704248
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF13C; BLyS Receptor 3; TNF Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor; BAFFR; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; Prolixin; CD268; BROMIX; Tumor Necrosis Factor Receptor Superfamily, Member
Cat. No.: HY-P72764
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF13C; BLyS Receptor 3; TNF Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor; BAFFR; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; Prolixin; CD268; BROMIX; Tumor Necrosis Factor Receptor Superfamily, Member
Cat. No.: HY-P76745
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF13C; BLyS Receptor 3; TNF Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor; BAFFR; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; Prolixin; CD268; BROMIX; Tumor Necrosis Factor Receptor Superfamily, Member
Cat. No.: HY-P7646
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF13C; BLyS Receptor 3; TNF Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor; BAFFR; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; Prolixin; CD268; BROMIX; Tumor Necrosis Factor Receptor Superfamily, Member
Cat. No.: HY-P78065
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF13C; BLyS Receptor 3; TNF Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor; BAFFR; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; Prolixin; CD268; BROMIX; Tumor Necrosis Factor Receptor Superfamily, Member
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
