DCI-Br-3
DCI-Br-3 is a rapid, highly sensitive, and selective probe to monitor thiols in the epileptic brain. (λex=537 nm, λem=675 nm).DCI-Br-3 can effectively cross the blood-brain barrier (BBB).
For research use only. We do not sell to patients.
- Formula: C25H20BrN3O2
- Molecular Weight:474.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
DCI-Br-3 (0-20 μM; 30 min; SH-SY5Y cells) increases intracellular fluorescence in a concentration-dependent manner and has a good response to thiols in SH-SY5Y cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/c mice (6 weeks of age)[1]
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Dosage:5 mg/kg
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Administration:intraperitoneal injection
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Result:Crossed the blood−brain barrier and had red fluorescence in BALB/c mice.
675
537
Chemical Information
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Molecular Weight 474.35
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Formula C25H20BrN3O2
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SMILES
N#C/C(C#N)=C1CC(C)(C)CC(/C=C/C2=CC=C(OC(C3=CC=NC=C3)=O)C(Br)=C2)=C\1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DCI-Br-3 Related Classifications
HY-151615 Related Classifications
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