EGFR/HER2-IN-16
EGFR/HER2-IN-16 (compound 12K) is an effective dual-target inhibitor of EGFR (IC50=6.15 nM) and HER-2 (IC50=9.78 nM) with anti-tumor activity. EGFR/HER2-IN-16 can inhibit the migration of SK-BR-3 cells, arrest the cell cycle in the G0/G1 phase, and induce apoptosis. EGFR/HER2-IN-16 exhibits good anti-proliferative activity against tumor cell models and has little damage to healthy cells. EGFR/HER2-IN-16 can be used in breast cancer research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C29H24BrN5O2
- Molecular Weight:554.44
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Help & FAQs
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Biologische Aktivität
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EGFR 6.15 nM (IC50) |
HER1 9.78 nM (IC50) |
Chemical Information
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Molecular Weight 554.44
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Formel C29H24BrN5O2
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SMILES
O=C(C1=CC=CC(Br)=C1)N2CCN(C3=CC=CC(NC4=C5C=C(C6=CC=CO6)C=CC5=NC=N4)=C3)CC2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
EGFR/HER2-IN-16 Related Classifications
HY-159519 Related Classifications
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