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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
BRD4 degrader-3
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "BRD4 degrader-3" in MCE Product Catalog:
Research Areas:
BRD4 degrader-3 is a molecular glue degrader targeting BRD4, with binding activity towards the BD1 and BD2 domains of BRD4. BRD4 degrader-3 regulates the activity of BRD4. BRD4 degrader-3 inhibits MYC expression in cancer cells. BRD4 degrader-3 suppresses cell proliferation. BRD4 degrader-3 can be used in research related to acute myeloid leukemia and prostate cancer .
Cat. No.: HY-135558
CAS No.: 2313234-00-1
Target:
Research Areas:
PROTAC BRD4 Degrader-3 is a VHL-recruiting PROTAC degrader that targets BRD4. PROTAC BRD4 Degrader-3 consists of a VHL E3 ubiquitin ligase ligand and a BRD4 inhibitor linked by a connector .
Cat. No.: HY-174210
Target:
Research Areas:
PROTAC BRD4 Degrader-3 is a potent BRD4 PROTAC degrader with DC50 values of 164 nM and 80 nM at 4 h and 24 h, respectively. PROTAC BRD4 Degrader-3 induces the ubiquitination and subsequent proteasomal degradation of BRD4 by recruiting the ubiquitin E3 ligase KLHDC2. PROTAC BRD4 Degrader-3 can be used in breast cancer research .
Cat. No.: HY-184670
CAS No.: 2313230-74-7
Target:
Research Areas:
VHL Ligand 8 is a von Hippel-Lindau (VHL) protein ligand. VHL Ligand 8 can be used in PROTAC synthesis-related research, such as for the synthesis of PROTAC BRD4 Degrader-3 (HY-135558) .
Cat. No.: HY-184671
CAS No.: 2313233-96-2
Research Areas:
VHL Ligand 41-CO-C10-NH2 is an E3 ligase ligand-linker conjugate for PROTAC synthesis. VHL Ligand 41-CO-C10-NH2 is the E3 ligase ligand-linker conjugate moiety of PROTAC BRD4 Degrader-3 (HY-135558) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
