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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
BuChE-IN-2
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "BuChE-IN-2" in MCE Product Catalog:
Cat. No.: HY-143413
CAS No.: 2745118-93-6
Target:
Research Areas:
BuChE-IN-2 is an excellent butyrylcholinesterase (BuChE) inhibitor (IC50s of 1.28 μM and 0.67 μM for BuChE and NO). BuChE-IN-2 can inhibit the aggregation of Aβ, ROS formation and chelate Cu 2+, exhibiting proper blood-brain barrier (BBB) penetration. BuChE-IN-2 has potential to research Alzheimer’s disease .
Cat. No.: HY-146142
CAS No.: 1946008-31-6
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AChE/BuChE-IN-2 (Compound 5f) is an orally active AChE and BuChE inhibitor with IC50 values of 0.72 μM and 0.16 μM, respectively. AChE/BuChE-IN-2 shows a non-competitive inhibition with AChE and shows potent self-induced β-amyloid (Aβ) aggregation inhibition with an IC50 of 62.52 μM. AChE/BuChE-IN-2 can cross the BBB .
Cat. No.: HY-116041
CAS No.: 20410-87-1
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Anabasamine is an alkaloid. Anabasamine can be isolated from the aerial parts of Anabasis aphylla L. As an inhibitor of Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE), Anabasamine has a pKi value of 3.49 against AChE and 2.08 against BuChE .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
