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Cloprostenol isopropyl ester

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100571
    Cloprostenol isopropyl ester

    		Prostaglandin Receptor Endocrinology
    Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM .
    <em>Cloprostenol</em> <em>isopropyl</em> ester
  • HY-116679
    17-trifluoromethylphenyl trinor Prostaglandin F2α

    17-Trifluoromethylphenyl trinor PGF2α

    		 Prostaglandin Receptor Endocrinology
    A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists.4 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF2α would act very much like the free acid of travoprost. 17-phenyl trinor PGF2α is a potent luteolytic, with a potency equal to or greater than fluprostenol and cloprostenol.
    17-trifluoromethylphenyl trinor Prostaglandin F2α

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