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Results for "

DFHBI

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

6

Fluorescent Dyes

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-110251
    DFHBI-1T
    15+ Cited Publications

    		 DNA Stain Others
    DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells .
    DFHBI-1T
  • HY-110250
    DFHBI
    5+ Cited Publications

    		 Fluorescent Dye Others
    DFHBI is a small molecule that resembles the chromophore of green fluorescent protein (GFP). DFHBI can be used for imaging RNA in living cells. . Spinach and DFHBI are essentially nonfluorescent when unbound, whereas the Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells (Ex/Em = 469/501 nm).
    DFHBI
  • HY-153845
    RNA Aptamer Broccoli sodium

    		Biochemical Assay Reagents Others
    RNA Aptamer Broccoli sodium is a 49-nucleotide nucleic acid aptamer that is much shorter than Spinach and Spinach2. It exhibits bright green fluorescence when binding to DFHBI or DFHBI-1T (a soluble analog of the green fluorescent protein label). RNA Aptamer Broccoli sodium can be used for RNA expression or localization in living cells .
    RNA Aptamer Broccoli sodium
  • HY-DY1047
    DFHBI-1T (solution)

    		DNA Stain Others
    DFHBI-1T (solution) is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells .
    Solvent and concentration: DMSO: 20 mM
    DFHBI-1T (solution)
  • HY-110251A
    DFHBI-2T

    		DNA Stain Others
    DFHBI-2T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=500 nm/523 nm). DFHBI-2T is used to image RNA in live cells .
    DFHBI-2T
  • HY-175397
    Dth

    DFHBI-thalidomide

    		 PROTACs NF-κB Early 2 Factor (E2F) Bcl-2 Family VEGFR Cancer
    Dth (DFHBI-thalidomide) is an RNA aptamer-based PROTAC degrader. Dth can degrade a variety of endogenous proteins (such as mCherry, p50, p65 and E2F1) by replacing the 3′ module on the RNA scaffold with the RNA aptamer corresponding to the target protein. Dth upregulates IκB-α and Bax, and downregulates Bcl-2 and VEGF. Dth generates green fluorescence upon binding to the Broccoli RNA aptamer, enabling the tracing of RNA scaffolds. Dth can be used in cancer-related research .
    Dth
  • HY-176801
    Oxide-DFHBI-demethyl

    		Ligands for Target Protein for PROTAC Cancer
    Oxide-DFHBI-demethyl is a target aptamer ligand (Ligand for Target Protein for PROTAC). Oxide-DFHBI-demethyl can be used for synthesis of RNA aptamer-based PROTAC Dth (HY-175397) .
    Oxide-DFHBI-demethyl
  • HY-176802
    Oxide-DFHBI-demethyl-C6-NH2

    		Target Protein Ligand-Linker Conjugates Cancer
    Oxide-DFHBI-demethyl-C6-NH2 is a Target Protein Ligand-Linker Conjugate that incorporates a target aptamer ligand (HY-176801) and a PROTAC linker (HY-79577), which recruits E3 ligases. Oxide-DFHBI-demethyl-C6-NH2 can be used for synthesis of RNA aptamer-based PROTAC Dth (HY-175397) .
    Oxide-DFHBI-demethyl-C6-NH2
  • HY-D2282
    DFHBI-BI

    		Fluorescent Dye Others
    DFHBI-BI is a mimic of the green fluorescence protein chromophore. DFHBI-BI can be bound and activated by Broccoli ( a fluorogenic RNA aptamer) with higher affinity. DFHBI-BI prevents thermal unfolding of Broccoli at 37°C in mammalian cells, subsequently forming more fluorescent Broccoli-BI complexes. The fluorescence wavelength is 559/635 nm .
    DFHBI-BI
  • HY-D3388
    BI dihydrochloride

    		Fluorescent Dye Drug Derivative Others
    BI dihydrochloride is a DFHBI (HY-110250) derivative for imaging of RNA in cells. BI dihydrochloride increases brightness and photostability of Broccoli aptamers in cells. BI dihydrochloride enables imaging of single Broccoli-tagged mRNAs in living cells. BI dihydrochloride exhibits peak excitation of 470 nm and peak fluorescence emission of 505 nm when bound to Broccoli.
    BI dihydrochloride

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