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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
DOTAGA dihydrochloride
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "DOTAGA dihydrochloride" in MCE Product Catalog:
Cat. No.: HY-156870
CAS No.: 1392478-00-0
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DOTAGA dihydrochloride is the dihydrochloride salt of DOTAGA, a DOTA-derived macrocyclic chelator. DOTAGA dihydrochloride serves as a synthetic precursor to DOTAGA-anhydride (HY-W087187), which is further used to construct bifunctional DOTA-type chelators suitable for bioconjugation and metal labeling. DOTAGA dihydrochloride is applicable in synthetic research on chelators for molecular imaging and radiometal labeling .
Cat. No.: HY-W087187
CAS No.: 1375475-53-8
DOTAGA-anhydride is a DOTA-based metal chelator that can bind to radionuclides and is used to prepare radionuclide drug conjugates (RDCs). DOTAGA-anhydride has been successfully used for labeling antibodies (e.g., Trastuzumab (HY-P9907)). DOTAGA-anhydride can be used for the synthesis of a bimodal tag for Single-photon emission computed tomography (SPECT) or PET/optical imaging .
Cat. No.: HY-164569
CAS No.: 1639843-65-4
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NH2 DOTA-GA is a DOTA-based metal chelator that can be used to prepare radionuclide drug conjugates (RDCs) whose carboxylic acid groups can complex metal ions, for example, NH2 DOTA-GA complexes Gd(III) ions.
Cat. No.: HY-159768A
CAS No.: 2882922-68-9
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DOTAGA.Glu.(FAPi) 2 is a FAPI homodimer in which a central glutamic acid (Glu) linker connects FAPI and a chelator. Radiolabeled with gallium- 68, lutetium- 177 or terbium- 161, DOTAGA.Glu.(FAPi) 2 is applicable to FAP-positive cancer PET imaging studies. DOTAGA.Glu.(FAPi) 2 is suitable for research related to prostate adenocarcinoma and recurrent glioblastoma multiforme .
Cat. No.: HY-173374
CAS No.: 3114056-16-2
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DOTAGA-FAP-2286-ALB is a derivative of Rofapitide tetraxetan (HY-147057). DOTAGA-FAP-2286-ALB is a selective fibroblast activation protein (FAP) inhibitor with an IC50 value of 67.5 nM. DOTAGA-FAP-2286-ALB enhances tumor retention via albumin interaction, prolonging blood circulation and improving radiometal complex stability (e.g., with 111In and 225Ac). DOTAGA-FAP-2286-ALB is promising for research of radionuclide therapy (TRT) of FAP-positive solid tumors .
Cat. No.: HY-176958
CAS No.: 2639365-74-3
OncoFAP-EN-DOTAGA is a FAP (fibroblast activation protein) targeting conjugate compound. OncoFAP-EN-DOTAGA can chelate radioactive isotopes (such as ) Ga-68 or fluorescent agent and can be used as a probe with targeting binding functions .
Cat. No.: HY-W087187G
CAS No.: 1375475-53-8
Cat. No.: HY-164364B
DOTAGA.(SA.FAPi)2 analogue TFA is a DOTAGA.(SA.FAPi)2 TFA (HY-164364A) analogue, in which the ligand and the chelator are identical to those of DOTAGA.(SA.FAPi)2 TFA. DOTAGA.(SA.FAPi)2 TFA is a potent dimeric fibroblast-activation protein inhibitor (FAPi) .
Cat. No.: HY-164364A
DOTAGA.(SA.FAPi)2 TFA is a potent dimeric fibroblast-activation protein inhibitor (FAPi). DOTAGA.(SA.FAPi)2 TFA has the potential for cancer diagnosis research .
Cat. No.: HY-164854
CAS No.: 914639-15-9
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(R)-DOTAGA2 (Compound 7) is a metal chelate ligand. (R)-DOTAGA2 can be used to evaluate blood volume changes in the heart and brain .
Cat. No.: HY-159767A
CAS No.: 2417089-06-4
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(S)-DOTAGA.(SA.FAPi)2 is a precursor for radiopharmaceutical labeling, which can be combined with radionuclides to create radionuclide drug conjugates (RDCs). RDCs have the capability to specifically target biomolecules and can be used in medical imaging .
Cat. No.: HY-185120A
CAS No.: 3084147-67-8
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ProX1-(SS)-DOTAGA (Compound 12b) is the unbound portion of the radionuclide in the compound and can be used for targeted delivery to diseases characterized by ACP3 expression .
Cat. No.: HY-185120
CAS No.: 3084147-79-2
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ProX1-(SS)-DOTAGA_R (Compound 25a) is the unbound radionuclide portion of the radiopharmaceutical and can be used for targeted delivery to diseases characterized by ACP3 expression .
Cat. No.: HY-153130
CAS No.: 2713429-51-5
Synonyms: (S)-PSMA I&T; (S)-PNT-2002
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(S)-Zadavotide guraxetan ((S)-PSMA I&T) is the S-isomer of EuK-Sub-kf-iodo-y-DOTAGA. (S)-Zadavotide guraxetan is a PSMA targeting compound .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
