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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
Dapagliflozin
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "Dapagliflozin" in MCE Product Catalog:
72
Target:
Research Areas:
Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
72
72 Cited Publications
Synonyms: BMS-512148 (2S)-1,2-propanediol, hydrate
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Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. Dapagliflozin ((2S)-1,2-propanediol, hydrate), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin ((2S)-1,2-propanediol, hydrate) induces HIF1 expression and attenuates renal IR injury .
Cat. No.: HY-I1120
CAS No.: 864070-37-1
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SGLT2-IN-1 (Compound 5) is an inhibitor for sodium-dependent glucose cotransporter (SGLT2), with IC50 of 33 nM in CHO cells transfected with human SGLT2. SGLT2-IN-1 is selective for SGLT2 over SGLT1. SGLT2-IN-1 is an active metabolite of dapagliflozinactive metabolite of dapagliflozin .
Dapagliflozin impurity is an enantiomer of Dapagliflozin which is a sodium-glucose transporter 2 inhibitor .
Synonyms: BMS-512148-d5
Cat. No.: HY-10450R
CAS No.: 461432-26-8
Synonyms: BMS-512148 (Standard)
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Dapagliflozin (Standard) is the analytical standard of Dapagliflozin. This product is intended for research and analytical applications. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
Cat. No.: HY-W018697
CAS No.: 42860-10-6
Synonyms: Dapagliflozin Impurity 50
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3-Bromo-4-chlorobenzoic acid (Dapagliflozin Impurity 50) is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-400785
CAS No.: 2452300-94-4
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Dapagliflozin impurity A (Compound A) is a dapagliflozin peroxide, a genotoxic impurity, can cause damage to human genetic material at very low concentrations, leading to genetic mutations and possibly tumorigenesis .
Cat. No.: HY-Z0437
CAS No.: 1632287-34-3
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Dapagliflozin methyl acetate is an orally active SGLT2 inhibitor. Dapagliflozin methyl acetate may be used in type 2 diabetes research .
Cat. No.: HY-122473
CAS No.: 1181681-43-5
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fluoro-Dapagliflozin, a structural analog of Dapagliflozin, is a selective SGLT2 inhibitor with Ki values of 5.3 nM and 330 nM for SGLT2 and SGLT1, respectively. fluoro-Dapagliflozin blocks glucose transport and glucose-coupled currents .
Cat. No.: HY-10450S5
Cat. No.: HY-137145
CAS No.: 1408245-02-2
Galacto-dapagliflozin is a selective inhibitor for hSGLT2 with Ki of 25 nM .
Synonyms: BMS-801576
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Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin (HY-10450), and is formed in the liver and kidney by uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9). Dapagliflozin is a selective inhibitor for SGLT2, that can be used to improve glycemic control and attenuate type 2 diabetes .
Cat. No.: HY-10450S2
CAS No.: 1224234-25-6
Synonyms: BMS-512148-d4
Cat. No.: HY-10450S3
Synonyms: BMS-512148-13C6
Cat. No.: HY-10450AR
CAS No.: 960404-48-2
Synonyms: BMS-512148 (2S)-1,2-propanediol, hydrate (Standard)
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Research Areas:
Dapagliflozin ((2S)-1,2-propanediol, hydrate) (Standard) is the analytical standard of Dapagliflozin ((2S)-1,2-propanediol, hydrate). This product is intended for research and analytical applications. Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. Dapagliflozin ((2S)-1,2-propanediol, hydrate), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin ((2S)-1,2-propanediol, hydrate) induces HIF1 expression and attenuates renal IR injury .
Cat. No.: HY-I1198
CAS No.: 2169998-23-4
Synonyms: Oxo-Dapagliflozin
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Dapagliflozin keto impurity (Oxo-dapagliflozin) is an oxo metabolite and related impurity of Dapagliflozin (HY-10450). Dapagliflozin keto impurity can be characterized by 1H NMR, 13C NMR and HRMS, and can be used in studies related to Dapagliflozin impurities and metabolites .
Cat. No.: HY-I1198R
CAS No.: 2169998-23-4
Synonyms: Oxo-Dapagliflozin (Standard)
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Dapagliflozin keto impurity (Standard) (Oxo-dapagliflozin (Standard)) is the analytical standard of Dapagliflozin keto impurity (HY-I1198). This product is intended for research and analytical applications. Dapagliflozin keto impurity (Oxo-dapagliflozin) is an oxo metabolite and related impurity of Dapagliflozin (HY-10450). Dapagliflozin keto impurity can be characterized by 1H NMR, 13C NMR and HRMS, and can be used in studies related to Dapagliflozin impurities and metabolites .
Cat. No.: HY-I1120R
CAS No.: 864070-37-1
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SGLT2-IN-1 (standard) is the analytical standard for SGLT2-IN-1. This product is used for research and analytical applications. SGLT2-IN-1 (Compound 5) is an inhibitor for sodium-dependent glucose cotransporter (SGLT2), with IC50 of 33 nM in CHO cells transfected with human SGLT2. SGLT2-IN-1 is selective for SGLT2 over SGLT1. SGLT2-IN-1 is an active metabolite of dapagliflozinactive metabolite of dapagliflozin.
Cat. No.: HY-I1118
CAS No.: 872980-38-6
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Dapagliflozin impurity 112 is an impurity of Dapagliflozin (HY-10450).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
