1351438-75-9
Chemical Structure
Dapagliflozin-3-O-β-D-glucuronide
Synonym(s): BMS-801576
- CAS No.: 1351438-75-9
- Formula:C27H33ClO12
- Molecular Weight:585.00
IUPAC Name: (2S,3S,4S,5R,6R)-6-(((2S,3S,4R,5R,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
InChIKey: ZYZULHSUKTZGTR-PTNNFGGUSA-N
SMILES: ClC1=C(CC2=CC=C(C=C2)OCC)C=C([C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O[C@]4([C@@H]([C@H]([C@@H]([C@H](O4)C(O)=O)O)O)O)[H])O)C=C1
Biological Activity: Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin (HY-10450), and is formed in the liver and kidney by uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9). Dapagliflozin is a selective inhibitor for SGLT2, that can be used to improve glycemic control and attenuate type 2 diabetes[1].
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Dapagliflozin-3-O-β-D-glucuronide | 99.0% | Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin (HY-10450), and is formed in the liver and kidney by uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9). Dapagliflozin is a selective inhibitor for SGLT2, that can be used to improve glycemic control and attenuate type 2 diabetes. | ||||||||||||||||||||
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