2. Search Result
Search Result
Results for "

Dihydropyrimidine

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Natural
Products

2

Isotope-Labeled Compounds

1

Antibodies

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W012926
    Dihydrouracil

    5,6-Dihydrouracil

    		 Endogenous Metabolite Metabolic Disease
    Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient .
    Dihydrouracil
  • HY-124062
    TAS-114
    2 Publications Verification

    		 Others Cancer
    TAS-114 is an orally active dual dUTPase/dihydropyrimidine dehydrogenase (DPD) inhibitor, can improving the therapeutic efficacy of fluoropyrimidine .
    TAS-114
  • HY-17469
    Gimeracil
    2 Publications Verification

    Gimestat

    		 Others Cancer
    Gimeracil, a component of an oral fluoropyrimidine derivative S-1, inhibits DNA DSB repair and is a potent inhibitor of DPYD (dihydropyrimidine dehydrogenase, DPD) .
    Gimeracil
  • HY-132888
    NCATS-SM4487

    		Others Metabolic Disease
    NCATS-SM4487 is a highly selective unique dihydropyrimidine inhibitor against GALK1, with an IC50 value of 0.05 μM.
    NCATS-SM4487
  • HY-W012926S1
    Dihydrouracil-d4

    5,6-Dihydrouracil-d4

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Dihydrouracil-d4 is the deuterium labeled Dihydrouracil . Dihydrouracil (HY-W012926), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient .
    Dihydrouracil-d4
  • HY-W012926S
    Dihydrouracil-13C4,15N2

    5,6-Dihydrouracil-13C4,15N2

    		 Endogenous Metabolite Metabolic Disease
    Dihydrouracil- 13C4, 15N2 is the 13C and 15N labeled Dihydrouracil[1]. Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient[2][3].
    Dihydrouracil-13C4,15N2
  • HY-W454906
    tDHU, acid

    		E3 Ligase Ligand-Linker Conjugates Cancer
    tDHU, acid is a dihydropyrimidinecereblon ligand that contains an E3 ligase ligand and a benzoic acid linker. tDHU, acid can be used as an E3 ubiquitin ligase ligand-Linker conjugate for the development of PROTACs .
    tDHU, acid
  • HY-138820
    SW02

    		HSP Neurological Disease
    SW02 is a potent activator of ATPase activity of Hsp70, with an EC50 of 150 μM. SW02 leads to accumulation of both total tau and phosphorylated tau (pTau) .
    SW02
  • HY-W014109
    (E)-5-(2-Bromovinyl)pyrimidine-2,4(1H,3H)-dione

    (E)-5-(2-Bromovinyl)uracil; BVU

    		 Others Infection
    (E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner. It enhances the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil (HY-90006) in a P388 murine leukemia model when administered at a dose of 200 μmol/kg, increasing survival time.
    (E)-5-(2-Bromovinyl)<em>pyrimidine</em>-2,4(1H,3H)-dione

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: