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Referencia número: HY-162788

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EGFR-IN-121

EGFR-IN-121 (compound 15) is a EGFR and VEGFR-2 dual inhibitor with IC₅₀s of 84 and 3.5 nM, respectively.

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No. CAS: 418799-16-3
Fòrmula: C₂₃H₂₆N₂O₅
Peso molecular:410.46

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

EGFR-IN-121 Chemical Structure

No. CAS: 418799-16-3

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Use of MCE Products

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Actividad biológica

Descripciòn

EGFR-IN-121 (compound 15) is a EGFR and VEGFR-2 dual inhibitor with IC₅₀s of 84 and 3.5 nM, respectively^[1].

Ver todos los productos específicos de isoformas EGFR :

Chemical Information

No. CAS 418799-16-3
Peso molecular 410.46
Fòrmula C₂₃H₂₆N₂O₅
SMILES

O=C(C1=C(C)NC(NC1C2=CC=C(OCC3=CC=CC=C3)C(OC)=C2)=O)OC(C)C
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Al-Wahaibi L H, et al. Design and Synthesis of New Dihydropyrimidine Derivatives with a Cytotoxic Effect as Dual EGFR/VEGFR-2 Inhibitors[J]. ACS Omega, 2024.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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EGFR-IN-121

Ver todos los productos específicos de isoformas EGFR

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

EGFR-IN-121 Related Classifications

HY-162788 Related Classifications

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